Zu "K01275" wurden 40 Artikel gefunden!
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L-Leucyl-L-Leucine methyl ester (hydrochloride)
Artikelnummer: Cay16008-100
L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid...
| Schlagworte: | LLME, LLOMe, L-leucyl-L-leucine, methyl ester, monohydrochloride |
| Anwendung: | Specific cytotoxin |
| CAS | 6491-83-4 |
| MW: | 294.8 D |
ab 44,00 €
Gly-Arg-AMC (hydrochloride)
Artikelnummer: TGM-T35932-10mg
Description: Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. Target: Others....
| Anwendung: | Fluorogenic cathepsin C substrate |
| CAS | 70274-78-1 |
| MW: | 424.89 D |
ab 93,00 €
L-Leucyl-L-Leucine methyl ester hydrochloride
Artikelnummer: TGM-T7739-100mg
Description: L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) is a lysosomal condensation product that exhibits cytotoxicity towards natural killer cells and CD4+ and CD8+ T lymphocytes. Target: Endogenous Metabolite, Others. Smiles: Cl.COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C. References:...
| Schlagworte: | Leu-Leu-ome hydrochloride |
| Anwendung: | Specific cytotoxin |
| CAS | 6491-83-4 |
| MW: | 294.81 D |
ab 43,00 €
Spinorphin
Artikelnummer: TGM-T8455-100mg
Description: Spinorphin is a heptapeptide, and is a potent enkephalin-degrading enzymes inhibitor. Target: Opioid Receptor. Smiles: CC(C)C[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H]([C@@H](C)O)C(O)=O. References: Ayar A ,...
| Anwendung: | Enkephalin-degrading enzyme inhibitor |
| CAS | 137201-62-8 |
| MW: | 877 D |
ab 135,00 €
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-02628-100ug
Description: Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function.
| Schlagworte: | Dipeptidyl transferase, Dipeptidyl peptidase I, Cathepsin J, Dipeptidyl peptidase 1, DPPI, Cathepsin C, DPP-I, Ctsc |
| MW: | 20.1 kD |
ab 284,00 €
Cathepsin C Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-00732-50ug
Description: Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated...
| Schlagworte: | PALS, PDON1, DPPI, JP, PLS, DPP-I, CPPI, cathepsin C, HMS, JPD, DPP1 |
| MW: | 51 kD |
599,00 €
Brensocatib
Artikelnummer: TGM-TQ0038-10mg
Description: Brensocatib (AZD7986) is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively). Target: Proteasome. Smiles: Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)cc1. References: Doyle K, et al. Discovery of Second...
| Schlagworte: | AZD7986, INS 1007 |
| Anwendung: | Targets cathepsin C [EC:3.4.14.1] (CTSC) |
| CAS | 1802148-05-5 |
| MW: | 420.46 D |
ab 67,00 €
Anti-Cleaved-CTSC (R394)
Artikelnummer: CSB-PA000029.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CTSC, Anti-CPPI, EC=3.4.14.1, AI047818 antibody, CATC antibody, CATC_HUMAN antibody, Cathepsin C antibody, Cathepsin... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-CTSC
Artikelnummer: CSB-PA115010.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CTSC. Antigen Species: Human
| Schlagworte: | Anti-CTSC, Anti-CPPI, EC=3.4.14.1, AI047818 antibody, CATC antibody, CATC_HUMAN antibody, Cathepsin C antibody, Cathepsin... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-CTSC
Artikelnummer: CSB-PA358929.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CTSC. Antigen Species: Human
| Schlagworte: | Anti-CTSC, Anti-CPPI, EC=3.4.14.1, AI047818 antibody, CATC antibody, CATC_HUMAN antibody, Cathepsin C antibody, Cathepsin... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Dipeptidyl peptidase 1 (Ctsc), partial, mouse, recombinant
Artikelnummer: CSB-EP006186MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 25-134aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: DTPANCTYPD LLGTWVFQVG PRSSRSDINC SVMEATEEKV VVHLKKLDTA YDELGNSGHF TLIYNQGFEI VLNDYKWFAF FKYEVRGHTA ISYCHETMTG WVHDVLGRNW....
| Schlagworte: | Ctsc, EC=3.4.14.1, Recombinant Mouse Dipeptidyl peptidase 1 (Ctsc), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 20.1 kD |
ab 292,00 €
Gly-Phe-beta-naphthylamide
Artikelnummer: Cay14634-50
Cathepsin C is a lysosomal cysteine protease with broad exopeptidase activity that progressively removes dipeptides from various protein and polypeptides substrates. Aside from its role in post-translational processing, cathepsins may also participate in apoptotic signaling pathways by targeting cytosolic caspases...
| Schlagworte: | H-Gly-Phe-BNA, glycyl-N-2-naphthalenyl-L-phenylalaninamide |
| Anwendung: | Cathepsin C substrate |
| CAS | 21438-66-4 |
| MW: | 347.4 D |
ab 78,00 €