Zu "K01201" wurden 42 Artikel gefunden!
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NEU
Lysosomal acid glucosylceramidase (GBA), human, recombinant
Artikelnummer: CSB-EP009289HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA...
| Schlagworte: | GC, SGTase, Beta-GC, Alglucerase, Imiglucerase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 75.6 kD |
ab 213,00 €
NEU
Lysosomal acid glucosylceramidase (GBA), human, recombinant
Artikelnummer: CSB-EP009289HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR...
| Schlagworte: | GC, SGTase, Beta-GC, Alglucerase, Imiglucerase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 61.1 kD |
ab 213,00 €
NEU
Lysosomal acid glucosylceramidase (GBA), human, recombinant
Artikelnummer: CSB-EP009289HUe1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-536aa. Protein Length: Full Length of Mature Protein. Tag Info: Tag-Free. Target Protein Sequence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI...
| Schlagworte: | GC, SGTase, Beta-GC, Alglucerase, Imiglucerase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 55.6 kD |
ab 355,00 €
NEU
Lysosomal acid Glucosylceramidase (Gba), mouse, recombinant
Artikelnummer: CSB-EP009289MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 20-515aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: AQPCIPKSFG YSSVVCVCNA SYCDSLDPVT LPALGTFSRY ESTRRGRRME LSVGAIQANR TGTGLLLTLQ PEKKFQKVKG FGGAMTDATA LNILALSPPT QKLLLRSYFS...
| Schlagworte: | SGTase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase, Cholesteryl-beta-glucosidase, Cholesterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 71.5 kD |
ab 283,00 €
NEU
Lysosomal acid Glucosylceramidase (Gba), mouse, recombinant
Artikelnummer: CSB-EP009289MOe1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 20-515aa. Protein Length: Full Length of Mature Protein. Tag Info: Tag-Free. Target Protein Sequence: AQPCIPKSFG YSSVVCVCNA SYCDSLDPVT LPALGTFSRY ESTRRGRRME LSVGAIQANR TGTGLLLTLQ PEKKFQKVKG FGGAMTDATA LNILALSPPT QKLLLRSYFS TNGIEYNIIR VPMASCDFSI...
| Schlagworte: | SGTase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase, Cholesteryl-beta-glucosidase, Cholesterol... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 55.6 kD |
ab 426,00 €
Conduritol B epoxide
Artikelnummer: Cay15216-5
Conduritol B epoxide (CBE) is an irreversible inhibitor of glucocerebrosidase, also known as acid beta-glucosidase, glucosylceramidase, GBA, or GBA1 (IC50 = 9 µM). Inhibition of this lysosomal glucosidase results in the accumulation of glucocerebroside without affecting cell viability, lysosomal enzyme release, or...
| Schlagworte: | CBE, 1,2-anhydro-myo-inositol |
| Anwendung: | Irreversible glucocerebrosidase inhibitor |
| CAS | 6090-95-5 |
| MW: | 162.1 D |
ab 73,00 €
Human GbA (Glucosidase Beta, Acid) ELISA Kit
Artikelnummer: ELK-ELK3085.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GbA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GbA. Next,...
| Schlagworte: | GBA, SGTase, Beta-GC, Alglucerase, Imiglucerase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
NCGC607
Artikelnummer: Cay21923-1
NCGC607 is a salicylic acid derivative and small molecule glucocerebrosidase (GCase) chaperone. A mutation in the GCase gene is found in patients with Gaucher disease and is the most common genetic risk factor for Parkinson's disease. In induced pluripotent stem cell-derived (iPSC) macrophages from patients with...
| Schlagworte: | 2-[2-[(4-iodophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-benzamide |
| Anwendung: | Glucocerebrosidase activator |
| CAS | 1462267-07-7 |
| MW: | 543.4 D |
ab 84,00 €
Isofagomine (D-tartrate)
Artikelnummer: Cay16137-5
Isofagomine (D-tartrate) is a competitive inhibitor of human lysosomal beta-glucosidase (Ki = 0.016-0.025 µM, IC50 = 0.06 µM). By interacting with the catalytic pocket of beta-glucosidase it acts as a chemical chaperone that increases the amount of beta-glucosidase by stabilizing and/or promoting the folding of the...
| Schlagworte: | 5R-(hydroxymethyl)-3R,4R-piperidinediol, mono 2S,3S-dihydroxybutanedioate |
| Anwendung: | Competitive glucosylceramidase (GBA) inhibitor |
| CAS | 957230-65-8 |
| MW: | 297.3 D |
ab 109,00 €
1-beta-D-Glucosylsphingosine (d18:1)
Artikelnummer: Cay23211-1
1-beta-D-Glucosylsphingosine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucocerebrosides (Cay-23207). They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of...
| Schlagworte: | 1-beta-D-Glucosylsphingosine (synthetic), Glucosyl-C18-Sphingosine, Glucosylsphingosine (d18:1),... |
| Anwendung: | Cytotoxic compound |
| CAS | 52050-17-6 |
| MW: | 461.6 D |
ab 139,00 €
LTI-291
Artikelnummer: Cay34305-5
LTI-291 is a CNS-penetrant allosteric activator of glucocerebrosidase (GCase). It increases the activity of wild-type human GCase by 25 and 130% when used at concentrations of 0.1 and 1 µM, respectively.Formal Name: 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-pyrazolo[1,5-a]pyrimidine-3-carboxamide. CAS Number:...
| Schlagworte: | 5,7-dimethyl-N-[trans-4-(pentyloxy)cyclohexyl]-pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Anwendung: | GCase allosteric activator |
| CAS | 1919820-28-2 |
| MW: | 358.5 D |
ab 229,00 €
Human Glucosylceramidase / GBA ELISA Kit
Artikelnummer: G-HUFI01329.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €