Zu "K01115" wurden 73 Artikel gefunden!
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CAY10594
Artikelnummer: TGM-T7280-100mg
Description: CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3beta/JNK axis. Target: Phospholipase. Smiles: O=C(NCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc2ccccc2c1. References: Lee SK, Bae GH, Kim YS,et al.A...
| Anwendung: | PLD2 inhibitor |
| CAS | 1130067-34-3 |
| MW: | 428.53 D |
ab 75,00 €
ML-298
Artikelnummer: TGM-T8966-100mg
Description: ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM). Target: Phospholipase. Smiles: Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(F)c(F)c2)CC1. References: Brown K A . Development of dual PLD1/2 and PLD2 selective inhibitors from a common...
| Schlagworte: | CID53393915, ML298 |
| Anwendung: | PLD2 inhibitor |
| CAS | 1426916-02-0 |
| MW: | 432.44 D |
ab 34,00 €
ML299
Artikelnummer: TGM-T8968-1mg
Description: ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively). Target: Phospholipase. Smiles: C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1cccc(F)c1)NC(=O)c1ccc(Br)cc1
| Schlagworte: | VU0463568, ML-299 |
| Anwendung: | PLD1 / PLD2 inhibitor |
| CAS | 1426916-00-8 |
| MW: | 489.38 D |
ab 142,00 €
Anti-Phospho-PLD1 (Thr147)
Artikelnummer: CSB-PA440926.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-PLD 1, Anti-phospho-hPLD1, Anti-phospho-Phospholipase D1, Anti-phospho-Choline phosphatase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Anti-Phospho-PLD2 (Tyr169)
Artikelnummer: CSB-PA983138.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-PLD 2, Anti-phospho-PLD1C, Anti-phospho-hPLD2, Anti-phospho-Phospholipase D2, Anti-phospho-Choline... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
CAY10594
Artikelnummer: Cay13207-5
Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
| Schlagworte: | N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)ethyl]-2-naphthalenecarboxamide |
| Anwendung: | PLD2 inhibitor |
| CAS | 1130067-34-3 |
| MW: | 428.5 D |
ab 69,00 €
VU0155069
Artikelnummer: Cay13206-5
Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
| Schlagworte: | CAY10593, N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-1-methylethyl]-2-naphthalenecarboxamide |
| Anwendung: | PLD1 inhibitor |
| MW: | 463 D |
ab 52,00 €
Anti-PLD1/Phospholipase D1
Artikelnummer: A305-241A
Protein function: Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. [The UniProt Consortium]
| Schlagworte: | Anti-PLD1, Anti-PLD 1, Anti-hPLD1, EC=3.1.4.4, Anti-Phospholipase D1, Anti-Choline phosphatase 1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
VU0359595
Artikelnummer: Cay10955-1
Phospholipase D (PLD) is an enzyme that cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1, and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
| Schlagworte: | CID-53361951, ML-270,... |
| Anwendung: | PLD1 inhibitor |
| MW: | 497.4 D |
ab 55,00 €
Halopemide
Artikelnummer: Cay13205-5
Halopemide is a potent inhibitor of phospholipase D (PLD), inhibiting human PLD1 and PLD2 in vitro (IC50 = 220 and 310 nM, respectively) and PLD activity in cells. Previously, halopemide has been found to inhibit dopamine receptors and was evaluated as a neuroleptic agent.Formal Name:...
| Schlagworte: | NSC 354856, R34301, N-[2-[4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]-ethyl]-4-fluoro-benzamide |
| Anwendung: | PLD inhibitor |
| CAS | 59831-65-1 |
| MW: | 416.9 D |
ab 61,00 €
ML-299
Artikelnummer: Cay17632-1
ML-299 is a dual inhibitor of phospholipase D1 (PLD1) and PLD2 (IC50s = 6 and 20 nM, respectively). It is selective for PLD1 and PLD2 over a panel of 65 receptors but also inhibits human-ether-a-go-go (hERG), also known as Kv11.1, as well as kappa- and µ-opioid receptors at 10 µM. ML-299 (1 and 10 µM) decreases...
| Schlagworte: | CID 56593087, 4-bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]-benzamide |
| Anwendung: | PLD1 / PLD2 inhibitor |
| CAS | 1426916-00-8 |
| MW: | 489.4 D |
ab 78,00 €
Human PLD2 / Phospholipase D2 ELISA Kit
Artikelnummer: G-HUFI00592.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €