Zu "K01047" wurden 264 Artikel gefunden!
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ONO-RS-082
Artikelnummer: TGM-T21815-1mg
Description: ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor. Target: Others. Smiles: CCCCCc1ccc(\C=C\C(=O)Nc2cc(Cl)ccc2C(O)=O)cc1. References: Banga H S , Simons E R , Brass L F , et al. Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and...
| Anwendung: | Reversible Ca2+-independent phospholipase A2 inhibitor |
| CAS | 99754-06-0 |
| MW: | 371.86 D |
ab 31,00 €
AZD2716
Artikelnummer: TGM-T30255-25mg
Description: AZD2716 is an effective selective phospholipase A2 inhibitor for the treatment of coronary artery and cardiovascular disease. Target: Others. Smiles: C(N)(=O)C1=C(C=C(CC2=CC=CC=C2)C=C1)C3=CC(C[C@H](C(O)=O)C)=CC=C3. References: An Enantioselective Hydrogenation of an Alkenoic Acid as a Key Step in the...
| Schlagworte: | AZD 2716, AZD-2716 |
| Anwendung: | SPLA2 inhibitor |
| CAS | 1845753-81-2 |
| MW: | 373.44 D |
ab 632,00 €
sPLA2 inhibitor 1
Artikelnummer: TGM-T27731-10mg
Description: KH064 is a sPLA2-IIA inhibitor of oral activity. Target: Others. Smiles: C([C@@H](NC(CCCCCCC1=CC=CC=C1)=O)CCC(O)=O)C2=CC=C(OCC3=CC=CC=C3)C=C2. References: Kim RR, Malde AK, Nematollahi A, Scott KF, Church WB. Molecular dynamics simulations reveal structural insights into inhibitor binding modes and...
| Schlagworte: | 5-BPP acid, KH 064, KH064, KH-064 |
| Anwendung: | sPLA2 inhibitor |
| CAS | 393569-31-8 |
| MW: | 487.63 D |
ab 93,00 €
Aristolochic acid A
Artikelnummer: TGM-T2801-10mg
Description: Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants. Target: Others, NF-kappaB. Smiles: COc1cccc2c1cc([N+]([O-])=O)c1c(cc3OCOc3c21)C(O)=O. References: Ma L, et al. J Ethnopharmacol. 2015...
| Schlagworte: | Aristolochic Acid I, Aristolochic Acid, Aristolochine, Aristolochin, TR 1736 |
| Anwendung: | Alkaloid, PLA2 inhibitor |
| CAS | 313-67-7 |
| MW: | 341.27 D |
ab 40,00 €
CAY10502
Artikelnummer: TGM-T37556-1mg
Description: Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2alpha) is a 85 kDa enzyme that plays a key role in the arachidonic cascade and the inflammatory response...
| Anwendung: | cPLA2 inhibitor |
| CAS | 888320-29-4 |
| MW: | 523.62 D |
ab 112,00 €
Arachidonoyl thio-PC
Artikelnummer: TGM-T37580-10mg
Description: Arachidonoyl Thio-PC is a substrate for various phospholipase A2s (PLA2s), including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 produces a free thiol that reacts with chromogenic reagents like DTNB (Ellman's reagent) and DTP, facilitating PLA2 activity quantitation....
| Anwendung: | PLA2 substrate |
| CAS | 146797-82-2 |
| MW: | 784.16 D |
ab 380,00 €
Lysophosphatidylethanolamines (egg)
Artikelnummer: TGM-T37999-10mg
Description: Lysophosphatidylethanolamines (egg) are the partial hydrolysis products of phosphatidylethanolamine. Target: Others. Smiles: O[C@@H](COP(OCC[NH3+])([O-])=O)COC([R])=O
| Anwendung: | Lysophospholipid mixture |
| CAS | 97281-40-8 |
ab 264,00 €
hnps-PLA Inhibitor
Artikelnummer: TGM-T4192-100mg
Description: Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). Target: LTR, Phospholipase. Smiles: C(C(N)=O)(=O)C=1C=2C(N(CC3=CC=CC=C3)C1CC)=CC=CC2OCC(N)=O. References: Meng H, Liu Y, Zhai Y, Lai L. Optimization of 5-hydroxytryptamines as dual function inhibitors...
| Anwendung: | Human nonpancreatic secretory Phospholipase A (hnps-PLA) inhibitor |
| CAS | 185298-58-2 |
| MW: | 379.41 D |
ab 52,00 €
CAY10590
Artikelnummer: TGM-T61168-10mg
Description: CAY10590 (GK115) is a compound that functions as an inhibitor of secreted phospholipase A2 (sPLA2). It is commonly employed in research related to chronic inflammatory kidney diseases [1]. Target: Others. Smiles: CCCC[C@H](CCC(O)=O)NC(=O)CCCCCCc1ccccc1
| Anwendung: | sPLA2 inhibitor |
| CAS | 1101136-50-8 |
| MW: | 347.49 D |
ab 392,00 €
Manoalide
Artikelnummer: TGM-T68752-100mg
Description: Manoalide, a sesterterpenoid compound, serves as a potent inhibitor of Phospholipase A2 (PLA2) and Phospholipase C (PLC). It exhibits anti-inflammatory and antibacterial properties. Target: Others. Smiles: O[C@H]1C(=CC(=O)O1)[C@@H]2O[C@@H](O)C(CC/C=C(/CCC=3C(C)(C)CCCC3C)\C)=CC2
| Anwendung: | Phospholipase A2 inhhibitor |
| CAS | 75088-80-1 |
| MW: | 416.55 D |
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1-Palmitoyl-sn-glycero-3-phosphocholine
Artikelnummer: TGM-T8712-100mg
Description: 1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine utilized in the design of fluorescent probes. Target: Others. Smiles: CCCCCCCCCC CCCCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C. References: D.B.J. Herrmann, E Ferber, P G Munder. Ether...
| Schlagworte: | 1-Hexadecanoyl-sn-glycero-3-phosphocholine |
| Anwendung: | Quantitative analytical standard, MaxSpec |
| CAS | 17364-16-8 |
| MW: | 495.63 D |
ab 40,00 €
LY433771
Artikelnummer: TGM-T84972-10mg
Description: LY433771 is a compound that inhibits the activity of Type X secretory phospholipase A2. Target: Others. Smiles: O(CC(O)=O)C1=C2C=3C(N(CC4CCCCC4)C2=CC=C1)=CC=CC3C(N)=O
| Schlagworte: | LSN433771 |
| Anwendung: | Type X sPLA2 inhibitor |
| CAS | 220862-64-6 |
| MW: | 380.44 D |
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