Zu "K00922" wurden 291 Artikel gefunden!
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LY294002
Artikelnummer: Cay70920-5
LY294002 is a multi-kinase inhibitor. It inhibits casein kinase 2 (CK2, IC50 = 0.098 µM), the PI3K subunits p110alpha, p110beta, p110delta, and p110gamma (IC50s = 0.497, 0.554, 0.331, and 3.8 µM, respectively), and DNA protein kinase (DNA-PK, IC50 = 6 µM), among other kinases, as well as CK1, GSK3alpha, and GSK3beta...
| Schlagworte: | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Anwendung: | PI3K inhibitor |
| CAS | 154447-36-6 |
| MW: | 307.3 D |
ab 35,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
569,00 €
Wortmannin
Artikelnummer: Cay10010591-1
By phosphorylating phosphatidylinositol, phosphoinositide 3-kinases (PI3K), activates diverse cellular functions, including cell growth, differentiation, survival, and motility. Wortmannin is a potent, cell-permeable, and irreversible inhibitor of PI3K enzymes (IC50 = 1-10 nM). However, the class II PI3Ks from...
| Schlagworte: | KY 12420,... |
| Anwendung: | PI3K inhibitor |
| CAS | 19545-26-7 |
| MW: | 428.4 D |
ab 60,00 €
NEU
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic...
Artikelnummer: CSB-EP017998HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 797-1068aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: NEIIFKNGDD LRQDMLTLQI IRIMENIWQN QGLDLRMLPY GCLSIGDCVG LIEVVRNSHT IMQIQCKGGL KGALQFNSHT LHQWLKDKNK GEIYDAAIDL FTRSCAGYCV ATFILGIGDR HNSNIMVKDD GQLFHIDFGH...
| Schlagworte: | PIK3CA, p110alpha, PI3Kalpha, PI3K-alpha, PI3-kinase subunit alpha, PtdIns-3-kinase subunit alpha, Phosphoinositide... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 33.9 kD |
ab 283,00 €
NEU
GNE-490
Artikelnummer: Cay41120-1
GNE-490 is an inhibitor of PI3K (IC50s = 3.5, 25, 5.2, and 15 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively). It is selective for PI3K over mTOR (IC50 = 740 nM) and a panel of 142 kinases at 1 µM. GNE-490 (0.4 µM) reduces cell migration by, the number of vessel outgrowths from, and induces...
| Schlagworte: | 2-(2-amino-4-methyl-5-pyrimidinyl)-alpha,alpha-dimethyl-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine-6-methanol |
| Anwendung: | PI3K inhibitor |
| CAS | 1033739-92-2 |
| MW: | 386.5 D |
ab 114,00 €
NEU
Anti-PIK3CA
Artikelnummer: CSB-PA003761.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PIK3CA, Anti-p110alpha, Anti-PI3Kalpha, Anti-PI3K-alpha, Anti-PI3-kinase subunit alpha, Anti-PtdIns-3-kinase subunit... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 106,00 €
NEU
Anti-PIK3CD
Artikelnummer: CSB-PA006089.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-PIK3CD, Anti-PI3Kdelta, Anti-p110delta, Anti-PI3K-delta, Anti-PI3-kinase subunit delta, Anti-PtdIns-3-kinase subunit... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
106,00 €
NEU
Anti-PIK3CB
Artikelnummer: CSB-PA110424.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIK3CB. Antigen Species: Human
| Schlagworte: | Anti-PIK3C1, Anti-PIK3CB, Anti-p110beta, Anti-PI3Kbeta, Anti-PI3K-beta, Anti-PI3-kinase subunit beta, Anti-PtdIns-3-kinase... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
NEU
Anti-PIK3CB Recombinant Monoclonal, clone 5A9
Artikelnummer: CSB-RA240122A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: PIK3CB. Antigen Species: Human
| Schlagworte: | Anti-PIK3C1, Anti-PIK3CB, Anti-p110beta, Anti-PI3Kbeta, Anti-PI3K-beta, Anti-PI3-kinase subunit beta, Anti-PtdIns-3-kinase... |
| Anwendung: | ELISA, WB, IP, , IP:1:200-1:1000 |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
NEU
Anti-PIK3CA Recombinant Monoclonal, clone 10E5
Artikelnummer: CSB-RA578819A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: PIK3CA. Antigen Species: Human
| Schlagworte: | Anti-PIK3CA, Anti-p110alpha, Anti-PI3Kalpha, Anti-PI3K-alpha, Anti-PI3-kinase subunit alpha, Anti-PtdIns-3-kinase subunit... |
| Anwendung: | ELISA, WB, IF, , IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 201,00 €
NEU
Anti-PIK3CD
Artikelnummer: CSB-PA193486.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIK3CD. Antigen Species: Human
| Schlagworte: | Anti-PIK3CD, Anti-PI3Kdelta, Anti-p110delta, Anti-PI3K-delta, Anti-PI3-kinase subunit delta, Anti-PtdIns-3-kinase subunit... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €
NEU
Anti-PIK3CD
Artikelnummer: CSB-PA597940.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PIK3CD. Antigen Species: Human
| Schlagworte: | Anti-PIK3CD, Anti-PI3Kdelta, Anti-p110delta, Anti-PI3K-delta, Anti-PI3-kinase subunit delta, Anti-PtdIns-3-kinase subunit... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 163,00 €