Zu "K00873" wurden 167 Artikel gefunden!
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Anti-PKM
Artikelnummer: ABS-KC-2237.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (PubMed:15996096, PubMed:1854723). The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to...
| Schlagworte: | Anti-Pyruvate kinase PKM, Anti-Cytosolic thyroid hormone-binding protein, Anti-CTHBP, Anti-Opa-interacting protein 3,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PKM
Artikelnummer: ABS-KC-2238.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (PubMed:15996096, PubMed:1854723). The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to...
| Schlagworte: | Anti-Pyruvate kinase PKM, Anti-Cytosolic thyroid hormone-binding protein, Anti-CTHBP, Anti-Opa-interacting protein 3,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PKM
Artikelnummer: ABS-KC-2239.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (PubMed:15996096, PubMed:1854723). The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to...
| Schlagworte: | Anti-Pyruvate kinase PKM, Anti-Cytosolic thyroid hormone-binding protein, Anti-CTHBP, Anti-Opa-interacting protein 3,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PKM
Artikelnummer: ABS-KC-2640.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (PubMed:15996096, PubMed:1854723). The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to...
| Schlagworte: | Anti-Pyruvate kinase PKM, Anti-Cytosolic thyroid hormone-binding protein, Anti-CTHBP, Anti-Opa-interacting protein 3,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-PKM
Artikelnummer: ABS-KC-6118.100
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (PubMed:15996096, PubMed:1854723). The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to...
| Schlagworte: | Anti-Pyruvate kinase PKM, Anti-Cytosolic thyroid hormone-binding protein, Anti-CTHBP, Anti-Opa-interacting protein 3,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, monkey |
ab 232,00 €
Anti-PKM2
Artikelnummer: E-D-AB-10309L.100
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP,generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor...
| Schlagworte: | Anti-p58, Anti-PKM, Anti-THBP1, Anti-OIP-3, Anti-CTHBP, Anti-Tumor M2-PK, Anti-Pyruvate kinase 2/3, Anti-Pyruvate kinase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 109,00 €
PKM2-IN-1
Artikelnummer: TGM-T4170-100mg
Description: PKM2-IN-1 (compound 3k) exhibits inhibitory activity against PKM2 with an IC50 of 2.95 µM, while the IC50 for PKM1 is 4-5 times higher. Target: PKM. Smiles: CC1=C(CSC(=S)N2CCCCC2)C(=O)c2ccccc2C1=O. References: Ning X, et al. Discovery of novel naphthoquinone derivatives as inhibitors of the tumor cell...
| Schlagworte: | PKM2 inhibitor, compound 3k |
| Anwendung: | PKM2 inhibitor |
| CAS | 94164-88-2 |
| MW: | 345.48 D |
ab 34,00 €
Micheliolide
Artikelnummer: TGM-T5688-100mg
Description: Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response. Target: NF-kappaB, COX, NOS. Smiles: CC1=C2CC[C@@](C)(O)[C@@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1. References: Sun Z, Li G, Tong T,et al.Micheliolide suppresses LPS-induced neuroinflammatory responses[J].PLoS One. 2017...
| Anwendung: | Bioactive sesquiterpene lactone, PKM2 activator |
| CAS | 68370-47-8 |
| MW: | 248.32 D |
ab 40,00 €
TEPP-46
Artikelnummer: TGM-T7214-100mg
Description: TEPP-46 (ML265) is a potent PKM2 activator (AC50 : 92 nM) showing little or no effect on PKM1, PKL and PKR,induces tetramerization and reduces tumor formation and size in a mouse xenograft model. . Target: PKM. Smiles: Cn1c2cc(sc2c2cnn(Cc3cccc(N)c3)c(=O)c12)S(C)=O. References: Walsh M J , Brimacombe K R...
| Schlagworte: | ML265 |
| Anwendung: | PKM2 activator |
| CAS | 1221186-53-3 |
| MW: | 372.46 D |
ab 42,00 €
ML202
Artikelnummer: TGM-T73525-10mg
Description: ML202 is a highly specific allosteric activator of human pyruvate kinase M2 (hPK-M2), enhancing the cooperativity of phosphoenolpyruvate (PEP) binding with negligible effect on adenosine diphosphate (ADP) binding. Target: Others. Smiles: CN1C2=C(C3=C1C(=O)N(CC4=CC(OC)=CC=C4)N=C3)SC(S(C)=O)=C2
| Anwendung: | PKM2 activator |
| CAS | 1221186-52-2 |
| MW: | 387.48 D |
ab 88,00 €
PKM2 Protein, Rat, Recombinant (His & Myc)
Artikelnummer: TGM-TMPH-03362-100ug
Description: PKM2 Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 61.8 kDa and the accession number is P11980.
| Schlagworte: | Pyruvate kinase PKM, Pyruvate kinase muscle isozyme, Pkm, Tyrosine-protein kinase PKM2, Threonine-protein kinase PKM2 |
| MW: | 61.8 kD |
ab 491,00 €
PKM2 Protein, Rat, Recombinant (E. coli, His & Myc)
Artikelnummer: TGM-TMPH-03363-100ug
Description: PKM2 Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.8 kDa and the accession number is P11980.
| Schlagworte: | Pyruvate kinase muscle isozyme, Tyrosine-protein kinase PKM2, Pkm, Pyruvate kinase PKM, Threonine-protein kinase PKM2 |
| MW: | 62.8 kD |
ab 359,00 €