Zu "K00665" wurden 75 Artikel gefunden!
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Anti-FASN
Artikelnummer: ABS-KC-6199.100
Protein function: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic...
| Schlagworte: | Anti-Fatty acid synthase, Anti-Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 232,00 €
Anti-FASN
Artikelnummer: ABS-KC-6425.100
Protein function: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic...
| Schlagworte: | Anti-Fatty acid synthase, Anti-Type I fatty acid synthase) [Includes: [Acyl-carrier-protein] S-acetyltransferase,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 232,00 €
Malonyl Coenzyme A (lithium salt)
Artikelnummer: Cay16455-5
Malonyl coenzyme A is a coenzyme A (CoA, Cay-16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of alpha-ketoglutarate across the mitochondrial membrane. Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA (Cay-16160). Fatty acid synthase...
| Schlagworte: | Malonyl-CoA, S-(hydrogen propanedioate) coenzyme A, lithium salt |
| Anwendung: | Fatty acid & polyketide synthesis intermediate |
| CAS | 108347-84-8 |
| MW: | 860.5 D |
ab 61,00 €
FT113
Artikelnummer: TGM-T7947-100mg
Description: FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity. Target: Fatty Acid Synthase. Smiles: OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1. References: Martin MW, et al. Discovery and optimization of novel piperazines as potent...
| Anwendung: | FASN inhibitor |
| CAS | 1630808-89-7 |
| MW: | 409.41 D |
ab 34,00 €
Fasnall benzenesulfonate
Artikelnummer: TGM-T85305-10mg
Description: Fasnall, a fatty acid synthase (FASN) inhibitor, exhibits an IC50 of 3.71 µM against the human recombinant enzyme. It halts tritiated acetate incorporation into lipids (IC50= 5.84 µM), boosts ceramide levels, and triggers lipid droplet formation in BT474 HER2+ breast cancer cells. Demonstrating...
| Anwendung: | FASN / FAS inhibitor |
| CAS | 2187367-11-7 |
| MW: | 496.6 D |
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FASN Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-06683-500ug
Description: FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327.
| Schlagworte: | SDR27X1, FAS, fatty acid synthase, OA-519 |
| MW: | 35.26 kD |
ab 599,00 €
FASN Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-06686-500ug
Description: FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096.
| Schlagworte: | fatty acid synthase, FAS, A630082H08Rik |
| MW: | 34.23 kD |
ab 599,00 €
BI-99179
Artikelnummer: Cay41307-1
BI-99179 is an inhibitor of fatty acid synthase type I (FAS-I, IC50 = 79 nM), a multifunctional enzyme that catalyzes the conversion of acetyl-coenzyme A (acetyl-CoA, Cay-16160) and malonyl-CoA (Cay-16455) to long-chain fatty acids. It is selective for FAS-I over 30 other enzymes, receptors, and ion channels at 10...
| Schlagworte: | N-[4-(2-benzoxazolyl)phenyl]-N-methyl-3S-[(1R-oxopropyl)amino]-cyclopentanecarboxamide |
| Anwendung: | FAS-I inhibitor |
| CAS | 1291779-76-4 |
| MW: | 391.5 D |
ab 54,00 €
TVB-3166
Artikelnummer: TGM-T17180-100mg
Description: TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively). Target: Apoptosis, Fatty Acid Synthase, Others. Smiles:...
| Anwendung: | FASN inhibitor |
| CAS | 1533438-83-3 |
| MW: | 384.47 D |
ab 34,00 €
Denifanstat
Artikelnummer: TGM-T15271-100mg
Description: Denifanstat (FASN-IN-2) is a fatty acid synthase (FASN) inhibitor (IC50=0.052 µM, EC50=0.072 µM) with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Target: Fatty Acid Synthase. Smiles: Cc1n[nH]c(n1)-c1cc(C(=O)N2CCC(CC2)c2ccc(cc2)C#N)c(C)cc1C1CCC1. References:...
| Schlagworte: | TVB2640, TVB-2640, FASN-IN-2 |
| Anwendung: | Targets fatty acid synthase, animal type [EC:2.3.1.85] (FASN) |
| CAS | 1399177-37-7 |
| MW: | 439.55 D |
ab 83,00 €
GSK2194069
Artikelnummer: TGM-T15429-2mg
Description: GSK2194069 is an active beta-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH. Target: Others,...
| Anwendung: | FASN inhibitor |
| CAS | 1332331-08-4 |
| MW: | 428.48 D |
148,00 €
Icaritin
Artikelnummer: TGM-T3398-100mg
Description: Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Icaritin has anti-multiple myeloma activity, mainly mediated by inhibiting...
| Schlagworte: | Cycloicaritin, Anhydroicaritin |
| Anwendung: | Anticancer agent, fatty acid synthase inhibitor |
| CAS | 118525-40-9 |
| MW: | 368.38 D |
ab 31,00 €