Zu "K00626" wurden 80 Artikel gefunden!
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Pellitorine
Artikelnummer: TGM-T21165-10mg
Description: Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist. Target: TRP/TRPV Channel. Smiles: CCCCC\C=C\C=C\C(=O)NCC(C)C. References: Rohm B, Riedel A, Ley JP, Widder S, Krammer GE, Somoza V. Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake...
| Schlagworte: | Pellitorin, AI3-19560 |
| Anwendung: | ACAT inhibitor |
| CAS | 18836-52-7 |
| MW: | 223.35 D |
ab 183,00 €
Penicillide
Artikelnummer: TGM-T36931-1mg
Description: Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT, IC50 = 22.9 µM). It is also an antagonist of oxytocin receptors (IC50 = 67 µM)....
| Anwendung: | ACAT Inhibitor |
| CAS | 55303-92-9 |
| MW: | 372.417 D |
ab 264,00 €
Terpendole C
Artikelnummer: TGM-T36776-1mg
Description: Terpendole C is an indole diterpene alkaloid fungal metabolite originally isolated from A. yamanashiensis and an inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT, IC50 = 2.1 µM in rat liver microsomes). It also inhibits ACAT in J774 macrophages (IC50 = 0.46 µM) without affecting cell...
| Anwendung: | ACAT Inhibitor |
| CAS | 156967-65-6 |
| MW: | 519.682 D |
ab 463,00 €
Terpendole E
Artikelnummer: TGM-T70289-100mg
Description: Terpendole E is an atypical L5 site inhibitor. Target: Others. Smiles: C[C@]12C3=C(C[C@@]1(CC[C@@]4([C@]2(C)CC[C@]5([C@@]4(C)[C@H](O)C[C@@H](C(C)(C)O)O5)[H])[H])[H])C=6C(N3)=CC=CC6
| Anwendung: | ACAT Inhibitor |
| CAS | 167427-23-8 |
| MW: | 437.61 D |
ab 4.585,00 €
ACAT2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-01302-10ug
Description: ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesis of cholesteryl esters which are part of lipoproteins containing apoB. ACAT2...
| Schlagworte: | Cytosolic acetoacetyl-CoA thiolase, Acetyl-CoA acetyltransferase cytosolic, ACAT2, Acetyl-CoA transferase-like protein, ACTL |
| MW: | 60 kD |
ab 180,00 €
ACAT1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-00875-100ug
Description: ACAT1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is P24752.
| Schlagworte: | Acetoacetyl-CoA thiolase, Acetyl-CoA acetyltransferase, mitochondrial, ACAT, MAT, EC:2.3.1.9 |
| MW: | 45.0 kD |
ab 278,00 €
ACAT2 Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-04813-100ug
Description: Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two enzymes are involved in storing cholesteryl esters as lipid droplets, in macrophage...
| Schlagworte: | acetyl-CoA acetyltransferase 2 |
| MW: | 43.3 kD |
ab 271,00 €
Lateritin
Artikelnummer: TGM-T25635-100mg
Description: Lateritin (Bassiatin) is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor from the mycelial cake of Gibberella lateritium. Bassiatin is the (3S,6R) isomer. Target: Acyltransferase. Smiles: CC(C)[C@H]1OC(=O)[C@@H](Cc2ccccc2)N(C)C1=O. References: Pettit RK,...
| Schlagworte: | Bassiatin |
| Anwendung: | Apoptosis inducer |
| CAS | 65454-13-9 |
| MW: | 261.32 D |
ab 252,00 €
Acetoacetyl-Coenzyme A (sodium salt hydrate)
Artikelnummer: Cay21219-10
Acetoacetyl-coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway. It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis. Acetoacetyl-CoA...
| Schlagworte: | Acetoacetyl-CoA, S-(3-oxobutanoate) coenzyme A, trisodium salt, tetrahydrate |
| Anwendung: | HMG-CoA precursor |
| MW: | 989.6 D |
ab 109,00 €
Pyripyropene A
Artikelnummer: TGM-T12592-100mg
Description: Pyripyropene A is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) with an IC50 of 0.07 µM. Target: Others. Smiles:...
| Anwendung: | ACAT2 inhibitor |
| CAS | 147444-03-9 |
| MW: | 583.63 D |
ab 3.995,00 €
RP 70676
Artikelnummer: TGM-T12767-100mg
Description: RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ). Target: Acyltransferase. Smiles: Cc1cc(C)n(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)n1. References: M.J. Ashton, et al. RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase...
| Anwendung: | ACAT inhibitor |
| CAS | 136609-26-2 |
| MW: | 416.58 D |
ab 91,00 €
Beauvericin
Artikelnummer: TGM-T14523-1mg
Description: Beauvericin, a Fusarium mycotoxin, inhibits acyl-CoA:cholesterol acyltransferase (ACAT) in rat liver microsomal enzyme assays with an IC50 value of 3 µM. Target: Acyltransferase, Others. Smiles:...
| Anwendung: | Apoptosis inducer |
| CAS | 26048-05-5 |
| MW: | 783.95 D |
ab 63,00 €