Zu "K00545" wurden 92 Artikel gefunden!
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Anti-COMT
Artikelnummer: ABS-KC-2556.100
Protein function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. [The UniProt Consortium]
| Schlagworte: | Anti-Catechol O-methyltransferase, COMT Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-COMT
Artikelnummer: ABS-KC-2779.100
Protein function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. [The UniProt Consortium]
| Schlagworte: | Anti-Catechol O-methyltransferase, COMT Antibody |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Nitecapone
Artikelnummer: TGM-T7831-100mg
Description: Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver). Target: Transferase, Others. Smiles: CC(=O)C(=Cc1cc(O)c(O)c(c1)[N+]([O-])=O)C(C)=O. References: P.T. Männistö, Kaakkola S . Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology, and...
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 116313-94-1 |
| MW: | 265.22 D |
ab 42,00 €
Tropolone
Artikelnummer: TGM-T8087-100mg
Description: Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion. Target: Tyrosinase. Smiles: O=C1C(O)=CC=CC=C1. References: Kahn V , Andrawis A . Inhibition of mushroom tyrosinase by tropolone[J]. Phytochemistry, 1985, 24(5):905-908.
| Anwendung: | Bioactive terpene |
| CAS | 533-75-5 |
| MW: | 122.12 D |
30,00 €
4-hydroxyestrone-4-methyl ether
Artikelnummer: TGM-T9455-1mg
Description: 4-hydroxyestrone-4-methyl ether (4-Methoxy Estrone) is the methylation of 4-OHE1, which is catalyzed by COMT. Target: Estrogen Receptor/ERR, Endogenous Metabolite. Smiles: C[C@](CC1)([C@@H](CC2)[C@H](CC3)[C@H]1c(cc1)c3c(OC)c1O)C2=O. References: Emons G, et al. Radioimmunoassay for 4-hydroxyestrone...
| Schlagworte: | 4-Methoxy Estrone |
| Anwendung: | Estrone active metabolite |
| CAS | 58562-33-7 |
| MW: | 300.39 D |
ab 114,00 €
3-METHOXY-DL-TYROSINE
Artikelnummer: TGM-T9492-100mg
Description: 3-METHOXY-DL-TYROSINE is a naturally occurring, non-essential amino acid found in the human body and many other organisms. It is a precursor to the neurotransmitter dopamine and is involved in the regulation of dopamine levels in the brain, with potential therapeutic applications in a variety of...
| Anwendung: | L-DOPA active metabolite |
| CAS | 7636-26-2 |
| MW: | 211.21 D |
ab 42,00 €
rac Metanephrine-d3 Hydrochloride Salt
Artikelnummer: TGM-TMIH-0473-10mg
Description: rac Metanephrine-d3 Hydrochloride Salt is a deuterated compound of rac Metanephrine Hydrochloride Salt. Smiles: Cl.[2H]C([2H])([2H])NCC(O)C1=CC(OC)=C(O)C=C1
| Anwendung: | GC-MS, LC-MS internal standard, quantification, epinephrine COMT metabolite |
| CAS | 1215507-88-2 |
| MW: | 236.71 D |
ab 247,00 €
COMT Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-05158-50ug
Description: COMT Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 31.5 kDa and the accession number is A0A140VJG8.
| Schlagworte: | HEL-S-98n, catechol-O-methyltransferase |
| MW: | 31.5 kD |
699,00 €
Ro 41-0960
Artikelnummer: TGM-T26106-10mg
Description: Ro 41-0960 is used as a reversible and orally-active COMT-inhibitor. Target: Others. Smiles: C(=O)(C1=CC(N(=O)=O)=C(O)C(O)=C1)C2=C(F)C=CC=C2. References: Gálvez-Llompart M, Recio MC, García-Domenech R, Gálvez J. Molecular topology: a strategy to identify novel compounds against ulcerative colitis. Mol...
| Schlagworte: | Ro41-0960, Ro-41-0960 |
| Anwendung: | COMT inhibitor |
| CAS | 125628-97-9 |
| MW: | 277.2 D |
ab 98,00 €
Tolcapone
Artikelnummer: TGM-T6708-100mg
Description: Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor employed as an adjunctive therapy with levodopa and carbidopa in the treatment of Parkinson's disease. Target: Apoptosis, Transferase, Beta Amyloid. Smiles: C(=O)(C1=CC(N(=O)=O)=C(O)C(O)=C1)C2=CC=C(C)C=C2. References: Zürcher G, et al....
| Schlagworte: | Ro 40-7592, Tasmar |
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 134308-13-7 |
| MW: | 273.24 D |
ab 33,00 €
2-Methoxyestrone
Artikelnummer: TGM-T13481-10mg
Description: 2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone [a nonuterotropic metabolite of estradiol]. Target: Endogenous Metabolite. Smiles: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3cc(OC)c(O)cc3CC[C@@]21[H]. References: Lewis KM, et al. pKa values of estrone,...
| Anwendung: | Estrone active metabolite |
| CAS | 362-08-3 |
| MW: | 300.39 D |
ab 57,00 €
Opicapone
Artikelnummer: TGM-T16398-100mg
Description: Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 µM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. Target: Transferase. Smiles:...
| Schlagworte: | BIA 9-1067 |
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 923287-50-7 |
| MW: | 413.17 D |
ab 60,00 €