Zu "K00541" wurden 44 Artikel gefunden!
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Bisubstrate Inhibitor 78
Artikelnummer: TGM-T36802-5mg
Description: Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT, IC50= 1.41 µM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide . Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine...
| Anwendung: | NNMT inhibitor |
| CAS | 2368247-39-4 |
| MW: | 507.54 D |
3.685,00 €
TRIA-662
Artikelnummer: TGM-T4853-100mg
Description: TRIA-662 (Nicotinamide Chloromethylate) is a niacin metabolite excreted via the urinary system. Target: Others, Endogenous Metabolite. Smiles: [Cl-].C[n+]1cccc(c1)C(N)=O. References: Zhao J, Zhang Y, Liu Y, et al. Antidepressant-like effects of 1-methylnicotinamide in a chronic unpredictable mild...
| Schlagworte: | 3-Carbamoyl-1-methylpyridinium Chloride, Nicotinamide Chloromethylate, 1-methylpyridin-1-ium-3-carboxamide hydrochloride,... |
| Anwendung: | Primary nicotinamide metabolite |
| CAS | 1005-24-9 |
| MW: | 172.62 D |
ab 40,00 €
N-Methylnicotinamide
Artikelnummer: TGM-T5233-1g
Description: N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction. Target: Endogenous Metabolite, Others. Smiles: CNC(=O)c1cccnc1. References: Pumpo, R., et al.: Am. J. Gastroenterol., 96, 1183 (2001)
| Schlagworte: | N-Methylpyridine-3-carboxamide, Nicotinic Acid Methylamide, N'-Methylnicotinamide |
| Anwendung: | Nicotinamide metabolite |
| CAS | 114-33-0 |
| MW: | 136.15 D |
37,00 €
JBSNF-000088
Artikelnummer: TGM-T8106-100mg
Description: JBSNF-000088 is an Nicotinamide N-methyltransferase (NNMT)inhibitor. It is used for the treatment of metabolic disorders. Target: Others. Smiles: C(N)(=O)C=1C=CC(OC)=NC1. References: Kannt A, Rajagopal S, Kadnur SV, Suresh J, Bhamidipati RK, Swaminathan S, Hallur MS, Kristam R, Elvert R, Czech J,...
| Schlagworte: | JBSNF000088 |
| Anwendung: | NNMT inhibitor |
| CAS | 7150-23-4 |
| MW: | 152.15 D |
ab 31,00 €
Nicotinamide N-methyltransferase (NNMT), human, recombinant
Artikelnummer: CSB-EP015906HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-264aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC LDGVKGDLLI DIGSGPTIYQ LLSACESFKE IVVTDYSDQN LQELEKWLKK EPEAFDWSPV VTYVCDLEGN RVKGPEKEEK LRQAVKQVLK...
| Schlagworte: | NNMT, EC=2.1.1.1, Nicotinamide N-methyltransferase, Recombinant Human Nicotinamide N-methyltransferase (NNMT) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 56.6 kD |
ab 219,00 €
1-Methylnicotinamide (chloride)
Artikelnummer: Cay16604-100
Nicotinamide is a precursor of NAD (Cay-16077) and NADP (Cay-10004675), which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide...
| Schlagworte: | N1-Methylnicotinamide chloride, Nicotinamide methochloride, Trigonellamide chloride,... |
| Anwendung: | Primary nicotinamide metabolite |
| CAS | 1005-24-9 |
| MW: | 172.6 D |
ab 44,00 €
JBSNF-000088
Artikelnummer: Cay29920-250
JBSNF-000088 is an inhibitor of nicotinamide N-methyltransferase (NNMT, IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively). It inhibits NNMT and reduces 1-methyl-nicotinamide (MNA) levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively). JBSNF-000088 (50 mg/kg) reduces visceral...
| Schlagworte: | 6-Methoxynicotinamide, NSC 70628, 6-methoxy-3-pyridinecarboxamide |
| Anwendung: | NNMT inhibitor |
| CAS | 7150-23-4 |
| MW: | 152.2 D |
ab 85,00 €
N-Methylnicotinamide
Artikelnummer: Cay21850-10
N-Methylnicotinamide is an isomer of nicotinamide. N-methylnicotinamide (20 mg/animal) increases urinary excretion of nicotinamide, 1-methylnicotinamide (Cay-16604), 1-methyl-2-pyridone-5-carboxamide, and 1-methyl-4-pyridone-3-carboxamide in mice in similar ratios as those excreted following nicotinamide...
| Schlagworte: | Nicotinic Acid Methylamide, N-Methylpyridine-3-carboxamide, NSC 66521, SR 4415, N-methyl-3-pyridinecarboxamide |
| Anwendung: | Nicotinamide metabolite |
| CAS | 114-33-0 |
| MW: | 136.2 D |
ab 67,00 €
Nicotinamide N-Methyltransferase (human, recombinant)
Artikelnummer: Cay15138-100
Nicotinamide N-Methyltransferase (NNMT) methylates nicotinamide and other pyridine containing compounds. NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nitrogen N1 of nicotinamide to produce 1-methylnicotinamide (MNA) and S-adenosylhomocysteine. MNA is a messenger molecule that increases neurite...
| Schlagworte: | NNMT, Nicotinamide N-methyltransferase, Nicotinamide N-methyltransferase |
| Anwendung: | Enzyme activity |
657,00 €
Bisubstrate Inhibitor 78
Artikelnummer: Cay28567-500
Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT, IC50 = 1.41 µM). It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide (Cay-11127). Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine...
| Schlagworte: | (S)-2-amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(naphthalen-2-ylmethyl)a... |
| Anwendung: | NNMT inhibitor |
| CAS | 2368247-39-4 |
| MW: | 507.5 D |
ab 227,00 €
Anti-NNMT, clone 11G11
Artikelnummer: ARG57060.50
Protein function: Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds. [The UniProt Consortium]
| Schlagworte: | Anti-NNMT, EC=2.1.1.1, Anti-Nicotinamide N-methyltransferase |
| Anwendung: | WB, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
518,00 €
Human NNMT / Nicotinamide N-methyltransferase ELISA Kit
Artikelnummer: G-HUFI01443.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €