Zu "K00512" wurden 44 Artikel gefunden!
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CYP17A1 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPH-02139-100ug
Description: A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as...
| Schlagworte: | Cytochrome P450 17A1, CYPXVII, 17-alpha-hydroxyprogesterone aldolase, Steroid 17-alpha-monooxygenase, Steroid... |
| MW: | 84.4 kD |
ab 193,00 €
Anti-CYP17A1
Artikelnummer: CSB-PA007590.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CYP17, Anti-CYPXVII, Anti-Cytochrome P450c17, Anti-Cytochrome P450-C17, Anti-Cytochrome P450 17A1, Anti-Steroid... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP17A1
Artikelnummer: CSB-PA074176.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP17A1. Antigen Species: Human
| Schlagworte: | Anti-CYP17, Anti-CYPXVII, Anti-Cytochrome P450c17, Anti-Cytochrome P450-C17, Anti-Cytochrome P450 17A1, Anti-Steroid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-CYP17A1 Recombinant Monoclonal, clone 5A9
Artikelnummer: CSB-RA554990A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: CYP17A1. Antigen Species: Human
| Schlagworte: | Anti-CYP17, Anti-CYPXVII, Anti-Cytochrome P450c17, Anti-Cytochrome P450-C17, Anti-Cytochrome P450 17A1, Anti-Steroid... |
| Anwendung: | ELISA, WB, IHC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 201,00 €
Anti-CYP17A1
Artikelnummer: CSB-PA939101.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP17A1. Antigen Species: Human
| Schlagworte: | Anti-CYP17, Anti-CYPXVII, Anti-Cytochrome P450c17, Anti-Cytochrome P450-C17, Anti-Cytochrome P450 17A1, Anti-Steroid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1),...
Artikelnummer: CSB-EP006392HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-508aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MWELVALLLL TLAYLFWPKR RCPGAKYPKS LLSLPLVGSL PFLPRHGHMH NNFFKLQKKY GPIYSVRMGT KTTVIVGHHQ LAKEVLIKKG KDFSGRPQMA TLDIASNNRK GIAFADSGAH WQLHRRLAMA TFALFKDGDQ...
| Schlagworte: | CYP17, CYPXVII, Cytochrome P450c17, Cytochrome P450-C17, Cytochrome P450 17A1, Steroid 17-alpha-monooxygenase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 84.4 kD |
ab 213,00 €
Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1),...
Artikelnummer: CSB-EP006392HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: AKKT+24-508aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AKKTGAKYPK SLLSLPLVGS LPFLPRHGHM HNNFFKLQKK YGPIYSVRMG TKTTVIVGHH QLAKEVLIKK GKDFSGRPQM ATLDIASNNR KGIAFADSGA HWQLHRRLAM ATFALFKDGD QKLEKIICQE...
| Schlagworte: | CYP17, CYPXVII, Cytochrome P450c17, Cytochrome P450-C17, Cytochrome P450 17A1, Steroid 17-alpha-monooxygenase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58.6 kD |
ab 213,00 €
Steroid 17-alpha-hydroxylase/17,20 lyase (Cyp17a1), rat,...
Artikelnummer: CSB-EP006392RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 1-507aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MWELVGLLLL ILAYFFWVKS KTPGAKLPRS LPSLPLVGSL PFLPRRGHMH VNFFKLQEKY GPIYSLRLGT TTTVIIGHYQ LAREVLIKKG KEFSGRPQMV TQSLLSDQGK GVAFADAGSS WHLHRKLVFS...
| Schlagworte: | Cyp17, CYPXVII, Cyp17a1, Cytochrome P450c17, Cytochrome P450-C17, Cytochrome P450 17A1, Steroid 17-alpha-monooxygenase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | rat |
| MW: | 73.3 kD |
ab 354,00 €
Abiraterone Acetate
Artikelnummer: Cay15148-5
Abiraterone acetate is an inhibitor of the cytochrome P450 (CYP) isoform CYP17A1 (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17alpha-hydroxylase activities, respectively). It is also a prodrug form of abiraterone (Cay-9002768). Abiraterone acetate reduces plasma testosterone levels, increases plasma...
| Schlagworte: | CB-7630, (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol, acetate ester |
| Anwendung: | CYP17A1 blocking |
| CAS | 154229-18-2 |
| MW: | 391.6 D |
ab 163,00 €
Abiraterone
Artikelnummer: Cay9002768-1
Abiraterone is an inhibitor of the cytochrome P450 (CYP) isoform CYP17A1 (IC50s = 0.0029 and 0.004 µM for the 17,20-lyase and 17alpha-hydroxylase activities, respectively) and active metabolite of abiraterone acetate (Cay-15148). It is formed from abiraterone acetate by arylacetamide deacetylase. Abiraterone is...
| Schlagworte: | CB-7598, (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol |
| Anwendung: | CYP17A1 inhibitor |
| CAS | 154229-19-3 |
| MW: | 349.5 D |
ab 43,00 €
17alpha-hydroxy Pregnenolone
Artikelnummer: Cay29181-100
17alpha-hydroxy Pregnenolone is a metabolite of pregnenolone (Cay-19864) and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA, Cay-15728). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated...
| Schlagworte: | 17-alpha-OH Pregnenolone, NSC 63853, 3beta,17-dihydroxy-pregn-5-en-20-one |
| Anwendung: | Pregnenolone metabolite, DHEA precursor |
| CAS | 387-79-1 |
| MW: | 332.5 D |
ab 60,00 €
Galeterone
Artikelnummer: Cay17586-5
The cytochrome P450 (CYP) isoform CYP17 is also known as steroid 17alpha-hydroxylase/17,20 lyase because it catalyzes both 17alpha-hydroxylase and 17,20 lyase reactions in the synthesis of steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids. Galeterone is a CYP17 inhibitor (IC50 = 300...
| Schlagworte: | TOK-001, 17-(1H-benzimidazol-1-yl)-androsta-5,16-dien-3beta-ol |
| Anwendung: | CYP17 inhibitor |
| CAS | 851983-85-2 |
| MW: | 388.6 D |
ab 32,00 €