Zu "K00509" wurden 235 Artikel gefunden!
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5,6-epoxy-13-cis Retinoic Acid
Artikelnummer: TGM-T37916-1mg
Description: 5,6-epoxy-13-cis Retinoic Acid is a metabolite of 13-cis retinoic acid. Target: Others. Smiles: C\C(\C=C\C12OC1(C)CCCC2(C)C)=C/C=C/C(/C)=C\C(O)=O
| Anwendung: | Metabolite |
| CAS | 81444-57-7 |
| MW: | 316.441 D |
880,00 €
TFAP
Artikelnummer: TGM-T4643-100mg
Description: TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor. Target: Endogenous Metabolite, COX. Smiles: Nc1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)nc1. References: Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg...
| Schlagworte: | N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide |
| Anwendung: | COX-1 inhibitor |
| CAS | 1011244-68-0 |
| MW: | 281.23 D |
ab 32,00 €
SC-560
Artikelnummer: TGM-T4101-100mg
Description: SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors. Target: COX. Smiles: COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C(F)(F)F. References: Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27,95(22):13313-8.
| Schlagworte: | SC560 |
| Anwendung: | COX-1 inhibitor |
| CAS | 188817-13-2 |
| MW: | 352.74 D |
ab 33,00 €
Ibuprofen sodium
Artikelnummer: TGM-T60292-25mg
Description: Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective inhibitor of COX-1 (IC50 = 13 µM) that inhibits cell proliferation and angiogenesis, and induces cell apoptosis. It is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor, used in research on pain, swelling, inflammation,...
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 31121-93-4 |
| MW: | 228.267 D |
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Sedanolide
Artikelnummer: TGM-T5763-100mg
Description: Sedanolide is a natural phthalide first isolated from seed oil of the Umbelliferae family, including celery. Target: Autophagy, Others. Smiles: CCCCC1OC(=O)C2=CCCCC12. References: Hsieh S L , Chen C T , Wang J J , et al. Sedanolide induces autophagy through the PI3K, p53 and NF-kappaB signaling...
| Anwendung: | COX inhibitor, mosquitocidal, nematicidal, antifungal |
| CAS | 6415-59-4 |
| MW: | 194.27 D |
ab 48,00 €
Aspirin calcium
Artikelnummer: TGM-T68847-100mg
Description: Aspirin calcium is the prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation...
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 69-46-5 |
| MW: | 398.38 D |
ab 1.491,00 €
Flurbiprofen sodium
Artikelnummer: TGM-T69082-100mg
Description: Flurbiprofen sodium is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase. Target: Others
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 56767-76-1 |
| MW: | 266.25 D |
ab 1.491,00 €
Oxyphenbutazone monohydrate
Artikelnummer: TGM-T72177-100mg
Description: Oxyphenbutazone monohydrate, a metabolite of Phenylbutazone, exhibits anti-inflammatory properties and acts as a non-selective COX inhibitor when taken orally. It also selectively targets and kills non-replicating Mycobacterium tuberculosis [1] [2]. Target: Others. Smiles:...
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 7081-38-1 |
| MW: | 342.39 D |
ab 1.491,00 €
Tenidap Sodium
Artikelnummer: TGM-T71264-100mg
Description: Tenidap Sodium is a COX/5-LOX inhibitor and cytokine-modulating anti-inflammatory agent. Target: Others. Smiles: [Na+].NC(=O)N1C(=O)\C(=C(/[O-])c2cccs2)c2cc(Cl)ccc12
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 119784-94-0 |
| MW: | 342.72 D |
ab 1.638,00 €
Phenylbutazone-d9
Artikelnummer: TGM-T71288-1mg
Description: Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, COX inhibitor |
| CAS | 1189479-75-1 |
| MW: | 317.43 D |
ab 289,00 €
Proglumetacin
Artikelnummer: TGM-T73666-50mg
Description: Proglumetacin, an orally active and potent cyclo-oxygenase inhibitor, inhibits the SARS-CoV Mpro (main protease of the SARS-CoV-2) with an AC50 of 8.9 µM, indicating its potential efficacy against SARS-CoV-2. It exhibits anti-inflammatory activity, making it suitable for research into conditions like...
| Anwendung: | Targets prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (PTGS1, COX1) |
| CAS | 57132-53-3 |
| MW: | 844.43 D |
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alpha-Demethylnaproxen
Artikelnummer: TGM-T7662-100mg
Description: alpha-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 µM for ovine COX-1 and -2, respectively). Target: COX. Smiles: COc1ccc2cc(CC(O)=O)ccc2c1. References: Johnson J L , Wimsatt J , Buckel S D , et al. Purification and Characterization of Prostaglandin H Synthase-2 from Sheep...
| Anwendung: | COX inhibitor |
| CAS | 23981-47-7 |
| MW: | 216.23 D |
ab 43,00 €