Zu "K00497" wurden 33 Artikel gefunden!
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21-Deoxycortisol-d8
Artikelnummer: TGM-TMID-0112-1mg
Description: 21-Deoxycortisol-d8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol has a CAS number of 641-77-0. 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11beta-hydroxylase.1,2Serum levels of 21-deoxycortisol are...
| Anwendung: | GC-MS, LC-MS internal standard, quantification, corticosteroid metabolite |
| CAS | 2479914-04-8 |
| MW: | 354.51 D |
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(-)-Ketoconazole
Artikelnummer: TGM-T13464L-2mg
Description: (-)-Ketoconazole is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers. Target: Others. Smiles: C([C@@]1(O[C@H](COC2=CC=C(C=C2)N3CCN(C(C)=O)CC3)CO1)C4=C(Cl)C=C(Cl)C=C4)N5C=CN=C5
| Schlagworte: | (-)-Ketoconazol, (-)-R 41400 |
| Anwendung: | Targets steroid 11beta-monooxygenase [EC:1.14.15.4] (CYP11B1) |
| CAS | 142128-57-2 |
| MW: | 531.43 D |
31,00 €
Cytochrome P450 11B1, mitochondrial (CYP11B1), human,...
Artikelnummer: CSB-EP006390HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 25-503aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: GTRAARVPRT VLPFEAMPRR PGNRWLRLLQ IWREQGYEDL HLEVHQTFQE LGPIFRYDLG GAGMVCVMLP EDVEKLQQVD SLHPHRMSLE...
| Schlagworte: | S11BH, CYPXIB1, Cytochrome P450C11, Cytochrome P-450c11, Cytochrome P450 11B1, mitochondrial, Steroid 11-beta-hydroxylase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 74.9 kD |
ab 283,00 €
Cytochrome P450 11B1, mitochondrial (CYP11B1), human,...
Artikelnummer: CSB-EP006390HUc7.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 25-503aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: GTRAARVPRT VLPFEAMPRR PGNRWLRLLQ IWREQGYEDL HLEVHQTFQE LGPIFRYDLG GAGMVCVMLP EDVEKLQQVD SLHPHRMSLE PWVAYRQHRG HKCGVFLLNG PEWRFNRLRL...
| Schlagworte: | S11BH, CYPXIB1, Cytochrome P450C11, Cytochrome P-450c11, Cytochrome P450 11B1, mitochondrial, Steroid 11-beta-hydroxylase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 61.9 kD |
ab 283,00 €
Anti-CYP11B1/CYP11B2
Artikelnummer: CSB-PA001924.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-S11BH, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP11B1
Artikelnummer: CSB-PA005156.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-S11BH, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
106,00 €
Anti-CYP11B1/CYP11B2
Artikelnummer: CSB-PA070172.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-S11BH, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
275,00 €
Anti-CYP11B1
Artikelnummer: CSB-PA248001.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP11B1. Antigen Species: Human
| Schlagworte: | Anti-S11BH, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Anti-CYP11B1
Artikelnummer: CSB-PA591028.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CYP11B1. Antigen Species: Human
| Schlagworte: | Anti-S11BH, Anti-CYPXIB1, Anti-Cytochrome P450C11, Anti-Cytochrome P-450c11, Anti-Cytochrome P450 11B1, mitochondrial,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 163,00 €
Metyrapone
Artikelnummer: Cay14994-1
Metyrapone is an inhibitor of the cytochrome P450 (CYP) enzyme 11beta-hydroxylase (IC50 = 7.83 µM), an enzyme involved in the final step of cortisol biosynthesis. It also induces Cyp1a1 and Cyp3a4 expression in rat hepatic microsomes and inhibits the activity of 11beta-hydroxysteroid dehydrogenase type 1...
| Schlagworte: | NSC 25265, SU 4885, 2-methyl-1,2-di-3-pyridinyl-1-propanone |
| Anwendung: | 11beta-hydroxylase inhibitor, CYP450 inhibitor |
| CAS | 54-36-4 |
| MW: | 226.3 D |
ab 34,00 €
Tetrahydro-11-deoxy Cortisol
Artikelnummer: Cay26501-10
Tetrahydro-11-deoxy cortisol (THS) is the primary urinary metabolite of 11-deoxycortisol. Urinary excretion of THS is elevated in patients with 11beta-hydroxylase deficiency, a condition resulting from mutations in the cytochrome P450 (CYP) isoform CYP11B1. Urinary levels of THS are also elevated in patients with...
| Schlagworte: | 5beta-Pregnane-3alpha,17alpha,21-triol-20-one, NSC 53901, Tetrahydrodeoxycortisol, THS,... |
| Anwendung: | Steroid 11-beta-hydroxylase mutation marker |
| CAS | 68-60-0 |
| MW: | 350.5 D |
ab 100,00 €
21-Deoxycortisol
Artikelnummer: Cay30873-1
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal gland via 11-hydroxylation by 11beta-hydroxylase. Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations in CYP2A21, the gene encoding steroid...
| Schlagworte: | 21-Dehydrohydrocortisone, 11beta,17-dihydroxy-pregn-4-ene-3,20-dione |
| Anwendung: | Corticosteroid metabolite |
| CAS | 641-77-0 |
| MW: | 346.5 D |
ab 61,00 €