Zu "K00463" wurden 180 Artikel gefunden!
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Anti-IDO1
Artikelnummer: E-D-AB-10451L.100
Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant,essential amino acid,l-tryptophan,along the kynurenine pathway. This protein is normally expressed in the dendritic cells,macrophages,microglia,eosinophils,fibroblasts,endothelial cells,and most tumor...
| Schlagworte: | Anti-IDO, Anti-IDO-1, Anti-Indoleamine 2,3-dioxygenase 1, Anti-Indoleamine-pyrrole 2,3-dioxygenase, IDO1 Polyclonal Antibody |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 109,00 €
Necrostatin-1
Artikelnummer: TGM-T1847-10mg
Description: Necrostatin-1 (Nec-1) is a specific RIP1 inhibitor and necrotic apoptosis inhibitor, which inhibits TNF-alpha-induced necrotic apoptosis and also inhibits IDO. Target: Indoleamine 2,3-Dioxygenase (IDO), Autophagy, Ferroptosis, RIP kinase. Smiles: CN1C(=S)NC(Cc2c[nH]c3ccccc23)C1=O. References: Hanna...
| Schlagworte: | Necrostatin 1, Nec-1 |
| Anwendung: | IDO inhibitor |
| CAS | 4311-88-0 |
| MW: | 259.33 D |
ab 31,00 €
IDO Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-06772-50ug
Description: IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession number is P28776.
| Schlagworte: | Ido, indoleamine 2,3-dioxygenase 1, Indo |
| MW: | 46.47 kD |
599,00 €
IDO Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01821-50ug
Description: IDO Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46 kDa and the accession number is P14902-1.
| Schlagworte: | IDO, indoleamine 2,3-dioxygenase 1, Indoleamine 2,3-dioxygenase, INDO, IDO-1 |
| MW: | 46 kD |
497,00 €
IDO2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-02803-50ug
Description: IDO2 belongs to the indoleamine 2,3-dioxygenase family. Indoleamine 2,3-dioxgyenase (IDO), is a cytosolic haem protein which, together with the hepatic enzyme tryptophan 2,3-dioxygenase, catalyzes the conversion of tryptophan and other indole derivatives to kynurenines. In addition to classic IDO...
| Schlagworte: | indoleamine 2,3-dioxygenase 2, INDOL1 |
| MW: | 46.2 kD |
599,00 €
IDO Protein, Human, Recombinant
Artikelnummer: TGM-TMPY-02928-50ug
Description: IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.
| Schlagworte: | Indoleamine 2,3-dioxygenase, IDO-1, INDO, IDO, indoleamine 2,3-dioxygenase 1 |
| MW: | 45.2 kD |
497,00 €
Navoximod
Artikelnummer: TGM-TQ0071-100mg
Description: Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM). Target: Indoleamine 2,3-Dioxygenase (IDO). Smiles: [H][C@@]1(CC[C@H](O)CC1)[C@H](O)C[C@H]1c2c(cccc2F)-c2cncn12. References: Mario R. Mautino, et al. Abstract 491: NLG919, a...
| Schlagworte: | GDC-0919, NLG-919 |
| Anwendung: | Targets indoleamine 2,3-dioxygenase [EC:1.13.11.52] (IDO, INDO) |
| CAS | 1402837-78-8 |
| MW: | 316.37 D |
ab 161,00 €
Indoximod
Artikelnummer: TGM-T6543-1g
Description: Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function....
| Schlagworte: | NLG-8189, Indoximod (NLG-8189), 1-Methyl-D-tryptophan |
| Anwendung: | Targets indoleamine 2,3-dioxygenase [EC:1.13.11.52] (IDO, INDO) |
| CAS | 110117-83-4 |
| MW: | 218.25 D |
ab 42,00 €
IDO1 and HDAC1 Inhibitor
Artikelnummer: TGM-T11625-25mg
Description: IDO1 and HDAC1 Inhibitor is a dual IDO1 and HDAC1 inhibitor (IC50s: 69.0 nM and 66.5 nM). Target: Others. Smiles: C(=NC1=CC(Br)=C(F)C=C1)(NO)C=2C(NCCNC(=O)C3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=NON2. References: Fang K, et al. Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase...
| Anwendung: | IDO1 / HDAC1 inhibitor |
| CAS | 2227044-16-6 |
| MW: | 597.4 D |
1.520,00 €
IDO1-IN-5
Artikelnummer: TGM-T11901-100mg
Description: IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. Target: Indoleamine 2,3-Dioxygenase (IDO), IDO. Smiles: C[C@@H](NC(=O)c1ccc(F)cc1)c1ccc2N(CCc2c1)C(=O)C1CCOCC1. References: Frank C. Dorsey, et al....
| Anwendung: | IDO1 inhibitor |
| CAS | 2166616-75-5 |
| MW: | 396.45 D |
ab 34,00 €
Epacadostat
Artikelnummer: TGM-T3548-100mg
Description: Epacadostat (INCB 024360) is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reducing tumor-associated regulatory T cells. Target: Indoleamine 2,3-Dioxygenase (IDO), IDO. Smiles:...
| Schlagworte: | IDO Inhibitor 1, INCB 024360 |
| Anwendung: | Targets indoleamine 2,3-dioxygenase [EC:1.13.11.52] (IDO, INDO) |
| CAS | 1204669-58-8 |
| MW: | 438.23 D |
ab 40,00 €
CAY10763
Artikelnummer: TGM-T36645-1mg
Description: CAY10763 is a dual inhibitor of indolamine 2,3-dioxygenase 1 (IDO1, IC50= 46 nM) and STAT3 activation.1It binds to STAT3 (Kd= 530 nM) and selectively reduces the levels of STAT3 phosphorylated at the tyrosine in position 705 (STAT3Y705) over phosphorylated STAT3S727, STAT1, and STAT5 in SKOV3 cells when...
| Schlagworte: | CAY10763 |
| Anwendung: | IDO1 / STAT3 activation dual inhibitor |
| CAS | 2364458-49-9 |
| MW: | 471.513 D |
ab 198,00 €