Zu "K00460" wurden 54 Artikel gefunden!
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Butyrolactone II
Artikelnummer: TGM-T124034-1mg
Description: Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6. Target: Others. Smiles: COC(=O)[C@]1(Cc2ccc(O)cc2)OC(=O)C(O)=C1c1ccc(O)cc1
| Anwendung: | Antibiotic, 5-Lipoxygenase (5-LOX) inhibitor |
| CAS | 87414-44-6 |
| MW: | 356.33 D |
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15-LOX-1 inhibitor 1
Artikelnummer: TGM-T36169-1mg
Description: 9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1, IC50 = 0.19 µM).1 It decreases LPS- and IFN-gamma-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 µM. 9c(i472) reduces LPS- and IFN-gamma-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7...
| Anwendung: | 15-lipoxygenase-1 (15-LO-1) inhibitor |
| CAS | 2349374-37-2 |
| MW: | 412.87 D |
ab 81,00 €
BLX3887
Artikelnummer: TGM-T37273-10mg
Description: BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1, IC50 = 32 nM in a cell-free enzyme assay).1 It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils...
| Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
| CAS | 934758-70-0 |
| MW: | 308.52 D |
ab 77,00 €
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
Artikelnummer: TGM-T37284-1mg
Description: 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid containing stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position, formed in human peripheral monocytes activated by the calcium ionophore A23187 through direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-LO....
| Anwendung: | Phospholipid |
| CAS | 947381-58-0 |
| MW: | 784.05 D |
ab 286,00 €
PD146176
Artikelnummer: TGM-T7530-100mg
Description: PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 µM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice. Target: Ferroptosis,...
| Schlagworte: | NSC168807 |
| Anwendung: | 15-LO inhibitor |
| CAS | 4079-26-9 |
| MW: | 237.32 D |
ab 41,00 €
4-MMPB
Artikelnummer: TGM-T8794-100mg
Description: 15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 µM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 µM and 19.1 µM for soybean 15-lipoxygenase (SLO) and human 15-lipoxygenase-1 (15-LOX-1), respectively. 4-MMPB has potential for the research of prostate...
| Schlagworte: | 15-Lipoxygenase Inhibitor 1 |
| Anwendung: | 15-LO inhibitor |
| CAS | 928853-86-5 |
| MW: | 313.42 D |
ab 69,00 €
17(S)-HDoTE
Artikelnummer: TGM-T84985-10mg
Description: 17(S)-HDoTE, a metabolite of adrenic acid, is synthesized through the action of 15-lipoxygenase (15-LO) via a 17-HpDoTE intermediate. Target: Others. Smiles: C(=C/[C@H](CCCCC)O)\C=C/C/C=C\C/C=C\CCCCCC(O)=O
| Schlagworte: | 17(S)-HDTA |
| Anwendung: | Adrenic acid metabolite |
| CAS | 105835-39-0 |
| MW: | 348.52 D |
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Nordihydroguaiaretic acid
Artikelnummer: TGM-TJS2190-100mg
Description: Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties....
| Schlagworte: | NDGA, Dihydronorguaiaretic Acid |
| Anwendung: | LO inhibitor |
| CAS | 500-38-9 |
| MW: | 302.36 D |
ab 26,00 €
ThioLox
Artikelnummer: TGM-T67908-100mg
Description: ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with an IC50 value of 12 µM, demonstrating significant anti-inflammatory and neuroprotective properties, including strong protection against glutamate toxicity. Target: Lipoxygenase. Smiles: C(NCCCC)(=O)C=1C=C(SC1N)C2=CC=CC=C2. References:...
| Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
| CAS | 1202193-89-2 |
| MW: | 274.38 D |
ab 31,00 €
Anti-ALOX15
Artikelnummer: CSB-PA192309.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALOX15. Antigen Species: Human
| Schlagworte: | Anti-LOG15, Anti-12-LOX, Anti-15-LOX, Anti-15-LOX-1, Anti-12/15-lipoxygenase, Anti-Linoleate 13S-lipoxygenase,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-ALOX15
Artikelnummer: CSB-PA624049.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALOX15. Antigen Species: Human
| Schlagworte: | Anti-LOG15, Anti-12-LOX, Anti-15-LOX, Anti-15-LOX-1, Anti-12/15-lipoxygenase, Anti-Linoleate 13S-lipoxygenase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Resolvin D1-d5
Artikelnummer: Cay11182-10
Resolvin D1-d5 (RvD1-d5) is intended for use as an internal standard for the quantification of RvD1 (Cay-10012554) by GC- or LC-mass spectrometry. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being...
| Schlagworte: | 17(S)-Resolvin D1-d5, RvD1-d5, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
| Anwendung: | GC-MS, LC-MS, Internal standard |
| CAS | 1881277-32-2 |
| MW: | 381.5 D |
ab 226,00 €