Zu "K00458" wurden 29 Artikel gefunden!
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Arachidonate 12-lipoxygenase, 12S-type (ALOX12), human,...
Artikelnummer: CSB-EP001617HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-663aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MGRYRIRVAT GAWLFSGSYN RVQLWLVGTR GEAELELQLR PARGEEEEFD HDVAEDLGLL QFVRLRKHHW LVDDAWFCDR ITVQGPGACA EVAFPCYRWV QGEDILSLPE GTARLPGDNA LDMFQKHREK...
| Schlagworte: | 12LO, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase, Platelet-type... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 79.8 kD |
ab 283,00 €
Human ALOX12 (Arachidonate-12-Lipoxygenase) ELISA Kit
Artikelnummer: ELK-ELK4754.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ALOX12. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ALOX12....
| Schlagworte: | 12LO, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate (13S)-lipoxygenase, Platelet-type... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
ML-355
Artikelnummer: Cay18537-1
Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
| Schlagworte: | N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-benzenesulfonamide |
| Anwendung: | 12-LO inhibitor |
| CAS | 1532593-30-8 |
| MW: | 441.5 D |
ab 66,00 €
Baicalein
Artikelnummer: Cay70610-50
Baicalein is a flavonoid originally isolated from the roots of S. baicalensis that has diverse biological activities. It inhibits human platelet 12-lipoxygenase (12-LO) and human reticulocyte 15-LO-1 (IC50s = 0.64 and 1.6 µM, respectively) but is less potent at 15-LO-1 when the detergent Triton-X is present (IC50 =...
| Schlagworte: | 5,6,7-trihydroxyflavone |
| Anwendung: | Lipid peroxidation inhibitor |
| CAS | 491-67-8 |
| MW: | 270.2 D |
ab 24,00 €
5,8,11-Eicosatriynoic Acid
Artikelnummer: Cay90200-5
5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM. 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM. At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases...
| Schlagworte: | 5,8,11-ETI, 5,8,11-eicosatriynoic acid |
| Anwendung: | LO inhibitor |
| CAS | 13488-22-7 |
| MW: | 300.4 D |
ab 114,00 €
12-Lipoxygenase (platelet-type, mouse recombinant)
Artikelnummer: Cay10341-25
12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also...
| Schlagworte: | Alox12, P-12LO, P-12LO, Alox12p, 12S-LOX, 12S-LOX, 12S-lipoxygenase, 12S-lipoxygenase, Lipoxin synthase 12-LO, Lipoxin... |
| Anwendung: | Enzyme activity |
| MW: | 76,4 kD |
489,00 €
CAY10698
Artikelnummer: Cay18582-1
Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
| Schlagworte: | 4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-N-2-thiazolyl-benzenesulfonamide |
| Anwendung: | 12-LO inhibitor |
| CAS | 684236-01-9 |
| MW: | 391.5 D |
ab 43,00 €
Human 12-LO / ALOX12 ELISA Kit
Artikelnummer: G-HUFI01663.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-12 Lipoxygenase
Artikelnummer: NSJ-R30558
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of...
| Schlagworte: | Anti-12LO, Anti-ALOX12, Anti-12S-LOX, EC=3.3.2.-, EC=1.13.11.31, Anti-12S-lipoxygenase, Anti-Lipoxin synthase 12-LO,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
12(S)-HETE-19,20-alkyne
Artikelnummer: Cay9001937-100
12(S)-HETE (Cay-34570) is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM. 12(S)-HETE-19,20-alkyne is a form of 12(S)-HETE with an omega-terminal alkyne. The terminal alkyne group can be used in...
| Schlagworte: | Click Tag(TM) 12(S)-HETE-19,20-alkyne, (S,5Z,8Z,10E,14Z)-12-hydroxyicosa-5,8,10,14-tetraen-19-ynoic acid |
| Anwendung: | Click chemistry reagent |
| MW: | 316.4 D |
ab 217,00 €
Anti-12 Lipoxygenase
Artikelnummer: ARG55210.100
Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)- hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize...
| Schlagworte: | Anti-12LO, Anti-ALOX12, Anti-12S-LOX, EC=3.3.2.-, EC=1.13.11.31, Anti-12S-lipoxygenase, Anti-Lipoxin synthase 12-LO,... |
| Anwendung: | FC, ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Human 12-LO (Arachidonate 12-Lipoxygenase) CLIA Kit
Artikelnummer: G-HUES01277.96
ELISA Type: CLIA. Sensitivity: 37.5 pg/mL. Range: 62.5--4000 pg/mL. Protein function: Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy...
| Schlagworte: | 12LO, ALOX12, 12S-LOX, EC=3.3.2.-, 12S-lipoxygenase, Lipoxin synthase 12-LO, Linoleate 13S-lipoxygenase, Platelet-type... |
| Anwendung: | CLIA |
| Spezies-Reaktivität: | human |
694,00 €