Zu "K00355" wurden 68 Artikel gefunden!
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beta-Lapachone
Artikelnummer: TGM-T6407-100mg
Description: beta-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase. Target: Autophagy, Apoptosis, IDO, Topoisomerase. Smiles: CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O. References: Li CJ, et al. J Biol Chem. 1993, 268(30), 22463-22468.
| Schlagworte: | Beta-Lapachone, SL-11001, NSC-26326, ARQ-501 |
| Anwendung: | Topoisomerase I and transglutaminase inhibitor |
| CAS | 4707-32-8 |
| MW: | 242.27 D |
ab 42,00 €
KL1333
Artikelnummer: TGM-T16342-100mg
Description: KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1alpha. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a...
| Schlagworte: | NQO1 activator 1 |
| Anwendung: | NQO1 substrate, beta-lapachone derivative |
| CAS | 1800405-30-4 |
| MW: | 240.26 D |
ab 94,00 €
Diminutol
Artikelnummer: TGM-T36358-5mg
Description: Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 µM), to destabilize microtubules and disrupt mitosis. At 50 µM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA...
| Anwendung: | Cell-permeable NQO1 inhibitor |
| CAS | 361431-33-6 |
| MW: | 386.51 D |
ab 122,00 €
NQO1 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02797-100ug
Description: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse,...
| Schlagworte: | Quinone reductase 1, Nqo1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H dehydrogenase [quinone] 1, Menadione reductase,... |
| MW: | 32.8 kD |
ab 339,00 €
NQO1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-03407-50ug
Description: NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species....
| Schlagworte: | QR1, NMOR1, DTD, DHQU, NMORI, NAD(P)H dehydrogenase, quinone 1, DIA4 |
| MW: | 33 kD |
385,00 €
Acenocoumarol
Artikelnummer: TGM-TQ0197-10mg
Description: Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant. Smiles: CC(=O)CC(c1ccc(cc1)[N+]([O-])=O)c1c(O)c2ccccc2oc1=O
| Anwendung: | Targets vitamin-K-epoxide reductase (warfarin-sensitive) [EC:1.17.4.4] (VKORC1) |
| CAS | 152-72-7 |
| MW: | 353.33 D |
ab 42,00 €
Anti-NQO1
Artikelnummer: CSB-PA003475.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-DTD, Anti-QR1, Anti-DIA4, Anti-NQO1, EC=1.6.5.2, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Menadione reductase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-NQO1
Artikelnummer: CSB-PA102829.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NQO1. Antigen Species: Human
| Schlagworte: | Anti-DTD, Anti-QR1, Anti-DIA4, Anti-NQO1, EC=1.6.5.2, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Menadione reductase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-NQO1
Artikelnummer: CSB-PA890070.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NQO1. Antigen Species: Human
| Schlagworte: | Anti-DTD, Anti-QR1, Anti-DIA4, Anti-NQO1, EC=1.6.5.2, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Menadione reductase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
KL1333
Artikelnummer: Cay39670-1
KL1333 is a substrate for NAD(P)H:quinone acceptor oxioreductase 1 (NQO1) and a derivative of the quinone beta-lapachone (Cay-15021). It is converted by NQO1 to NAD+ and increases the ratio of NAD+ to NADH in a cell-free assay, as well as C2C12 and L6 myoblasts, when used at concentrations of 1, 1, or 2 µM,...
| Schlagworte: | 2-(1-methylethyl)-3H-naphth[1,2-d]imidazole-4,5-dione |
| Anwendung: | NQO1 substrate, beta-lapachone derivative |
| CAS | 1800405-30-4 |
| MW: | 240.3 D |
ab 67,00 €
![NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse, recombinant](https://www.biomol.com/media/image/c3/07/3b/CSB-YP717562MO-1_200x200.jpg "NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse, recombinant")
NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse,...
Artikelnummer: CSB-YP717562MO.1
Organism: Mus musculus (Mouse). Source: Yeast. Expression Region: 2-274aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AARRALIVLA HSEKTSFNYA MKEAAVEALK KRGWEVLESD LYAMNFNPII SRNDITGELK DSKNFQYPSE SSLAYKEGRL SPDIVAEHKK LEAADLVIFQ FPLQWFGVPA ILKGWFERVL...
| Schlagworte: | QR1, DTD, Dia4, Nqo1, EC=1.6.5.2, Azoreductase, DT-diaphorase, Quinone reductase 1, Menadione reductase, Phylloquinone... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | mouse |
| MW: | 32.8 kD |
ab 347,00 €
![NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse, recombinant](https://www.biomol.com/media/image/92/a3/76/CSB-EP717562MO-1_200x200.jpg "NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse, recombinant")
NAD (P)H dehydrogenase [quinone] 1 (Nqo1), mouse,...
Artikelnummer: CSB-EP717562MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 2-274aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: AARRALIVLA HSEKTSFNYA MKEAAVEALK KRGWEVLESD LYAMNFNPII SRNDITGELK DSKNFQYPSE SSLAYKEGRL SPDIVAEHKK LEAADLVIFQ FPLQWFGVPA...
| Schlagworte: | QR1, DTD, Dia4, Nqo1, EC=1.6.5.2, Azoreductase, DT-diaphorase, Quinone reductase 1, Menadione reductase, Phylloquinone... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 43.8 kD |
ab 292,00 €