Zu "K00106" wurden 64 Artikel gefunden!
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6-Formylpterin
Artikelnummer: Cay14247-1
Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and...
| Schlagworte: | 6-FP, 2-Amino-6-formylpteridin-4-one, Pterin-6-aldehyde, 2-amino-3,4-dihydro-4-oxo-6-pteridinecarboxaldehyde |
| Anwendung: | Intracellular H2O2 generator in cells expressing XO |
| CAS | 712-30-1 |
| MW: | 191.1 D |
ab 108,00 €
Tisopurine
Artikelnummer: TGM-T71808-100mg
Description: Tisopurine is a drug used in the treatment of gout in some countries. It reduces uric acid production through inhibiting an early stage in its production. Target: Others. Smiles: S=C1N=CNC2=NNC=C12
| Anwendung: | Targets xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] (XDH) |
| CAS | 5334-23-6 |
| MW: | 152.18 D |
ab 1.520,00 €
amflutizole
Artikelnummer: TGM-T8567-100mg
Description: Amflutizole used for the treatment of gout, and is a Xanthine oxidase inhibitor. Target: Xanthine Oxidase. Smiles: Nc1c(snc1-c1cccc(c1)C(F)(F)F)C(O)=O. References: Phillis J W , Sen S , Cao X . Amflutizole, a xanthine oxidase inhibitor, inhibits free radical generation in the ischemic/reperfused rat...
| Anwendung: | Targets xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] (XDH) |
| CAS | 82114-19-0 |
| MW: | 288.246 D |
ab 133,00 €
Lucigenin
Artikelnummer: TGM-T19023-1mL
Description: Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells. Target: Others. Smiles: [O-][N+]([O-])=O.[O-][N+]([O-])=O.C[n+]1c2ccccc2c(-c2c3ccccc3[n+](C)c3ccccc23)c2ccccc12. References: Li Y, et al. Validation of...
| Schlagworte: | NSC-151912, L-6868 |
| Anwendung: | Superoxide indicator, chloride indicator |
| CAS | 2315-97-1 |
| MW: | 510.5 D |
30,00 €
Allopurinol Sodium
Artikelnummer: TGM-T6376-100mg
Description: Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 µM. Target: ROS. Smiles: [Na+].O=C1NC=NC2=C1C=NN2. References: Mitsuboshi S, et al. J Pharm Health Care Sci. 2015 Oct 6,1:28.
| Schlagworte: | Sodium allopurinol, Allopurinol sodium salt |
| Anwendung: | Targets xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] (XDH) |
| CAS | 17795-21-0 |
| MW: | 159.1 D |
ab 31,00 €
Isorhamnetin
Artikelnummer: TGM-T2836-100mg
Description: Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LDL via inhibition of lectin-like ox-LDL receptor-1 upregulation, interference of...
| Schlagworte: | 3-methylquercetin, 3'-Methylquercetin, Isorhamnetol, 3'-Methoxyquercetin |
| Anwendung: | Xanthine oxidase inhibitor, MATE1 inhibitor, antioxidant |
| CAS | 480-19-3 |
| MW: | 316.26 D |
ab 34,00 €
6-Formylpterin
Artikelnummer: TGM-T35976-100mg
Description: 6-Formylpterin (Pterin-6-aldehyde) is an inhibitor of Xanthine Oxidase (Ki ~0.6 nM) with potent neuroprotective effects against transient IRI in gerbils.6-Formylpterin induces intracellular ROS generation in HL-60 cells as well as apoptosis ( 6-Formylpterin inhibits the expression of iNOS, produces...
| Schlagworte: | Pterin-6-aldehyde, 6 Formylpterin |
| Anwendung: | Intracellular H2O2 generator in cells expressing XO |
| CAS | 712-30-1 |
| MW: | 191.15 D |
ab 37,00 €
Xanthine dehydrogenase Inhibitor 1
Artikelnummer: TGM-T50071-100mg
Description: 5-amino-1-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile is a compound used as a molecular structural unit and is considered to be an inhibitor of enzymes such as COX-2, 5-LOX, etc., and possesses a wide range of biochemical and physiological effects including antitumor activity,...
| Anwendung: | Xanthine dehydrogenase inhibitor |
| CAS | 80025-67-8 |
| MW: | 252.2 D |
ab 75,00 €
Purpurin
Artikelnummer: TGM-T5648-100mg
Description: Purpurin (Verantin) was a reversible and competitive inhibitor of MAO-A with a Ki value of 0.422µM. it exhibits anti-angiogenic, antifungal, antibiotic, and antioxidative activities. Target: Antibiotic, Antifungal, MAO, Antibacterial. Smiles: Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O. References: Lee H W ,...
| Schlagworte: | 1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin |
| Anwendung: | Xanthine oxidase inhibitor |
| CAS | 81-54-9 |
| MW: | 256.21 D |
ab 31,00 €
Xanthine Oxidase Fluorometric Assay Kit
Artikelnummer: Cay10010895-96
Xanthine oxidase (XO) catalyzes the hydroxylation of hypoxanthine to xanthine and then further catalyzes the oxidation of xanthine to uric acid. When oxidizing NADH, XO generates superoxide, a powerful reactive oxygen species. Excessive amounts of superoxide can lead to cell degeneration and death. XO is found...
| Schlagworte: | Xanthine Oxidoreductase Assay Kit, XO Assay Kit |
| Anwendung: | Fluorescence |
380,00 €
Febuxostat
Artikelnummer: LKT-F1607.50
Xanthine oxidase inhibitor.
| Schlagworte: | 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid |
| Anwendung: | Xanthine dehydrogenase/oxidase inhibitor |
| CAS | 144060-53-7 |
| MW: | 316.37 D |
ab 76,00 €
Lucigenin
Artikelnummer: Cay14872-50
Lucigenin is a chemiluminescent probe used to detect superoxide production and the presence of chloride. It can be used to detect superoxide production by enzymatic and cellular sources. It is a sensitive method that has been applied to the monitoring of superoxide production from xanthine oxidase, microsomal NADPH...
| Schlagworte: | L-6,868, NSC 151912, 10,10'-dimethyl-9,9'-biacridinium, dinitrate |
| Anwendung: | Superoxide indicator, chloride indicator |
| CAS | 2315-97-1 |
| MW: | 510.5 D |
ab 44,00 €