Zu "K00069" wurden 52 Artikel gefunden!
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SW033291
Artikelnummer: TGM-T2121-1mg
Description: SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. Target: Dehydrogenase. Smiles: CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1. References: Zhang Y, et al. Science. 2015, 348(6240), aaa2340.
| Anwendung: | 15-PGDH inhibitor |
| CAS | 459147-39-8 |
| MW: | 412.59 D |
ab 34,00 €
CAY10397
Artikelnummer: TGM-T26956-1mg
Description: CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. Target: Others. Smiles: N(=NC1=CC=C(C(OCC)=O)C=C1)C2=CC(CC(O)=O)=C(O)C=C2. References: Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA....
| Anwendung: | 15-hydroxy PGDH inhibitor |
| CAS | 78028-01-0 |
| MW: | 328.32 D |
ab 147,00 €
ML-148
Artikelnummer: TGM-T38163-100mg
Description: ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways. Target: Dehydrogenase. Smiles:...
| Anwendung: | Potent, selective, competitive HPGD inhibitor |
| CAS | 451496-96-1 |
| MW: | 319.4 D |
ab 55,00 €
15-PGDH-IN-1
Artikelnummer: TGM-T72950-10mg
Description: 15-PGDH-IN-1 is an orally active, potent inhibitor of 15-PGDH, exhibiting significant inhibitory activity against recombinant human 15-PGDH with an IC50 value of 3 nM. This compound is utilized in the research of tissue repair and regeneration. Target: Others. Smiles:...
| Anwendung: | 15-PGDH inhibitor |
| CAS | 2241676-74-2 |
| MW: | 398.46 D |
ab 166,00 €
13,14-dihydro-15-keto Prostaglandin E2
Artikelnummer: TGM-T84586-10mg
Description: 13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) serves as the predominant metabolite of PGE2 in plasma, created through a 15-keto PGE2 intermediate by the action of 15-oxo-PG Delta13 reductase. Unlike its precursor PGE2, this compound exhibits poor binding affinity towards EP2 and...
| Schlagworte: | 13,14-dihydro-15-keto PGE2 |
| Anwendung: | Bioactive lipid assays |
| CAS | 363-23-5 |
| MW: | 352.5 D |
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15-PGDH Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-01264-50ug
Description: 15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1.
| Schlagworte: | PGDH1, hydroxyprostaglandin dehydrogenase 15-(NAD), SDR36C1, PHOAR1, 15-PGDH, PGDH |
| MW: | 29.7 kD |
599,00 €
15-PGDH Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-02273-50ug
Description: 15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1.
| Schlagworte: | AV026552, hydroxyprostaglandin dehydrogenase 15-(NAD), 15-PGDH |
| MW: | 30.6 kD |
599,00 €
13,14-dihydro-15-keto Prostaglandin E2
Artikelnummer: Cay14650-1
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
| Schlagworte: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 363-23-5 |
| MW: | 352.5 D |
ab 95,00 €
Anti-HPGD
Artikelnummer: CSB-PA994843.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HPGD. Antigen Species: Human
| Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin dehydrogenase [NAD(+)],... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-HPGD
Artikelnummer: CSB-PA166476.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HPGD. Antigen Species: Human
| Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin dehydrogenase [NAD(+)],... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
SW033291
Artikelnummer: Cay18040-5
The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo. It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection....
| Schlagworte: | 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine |
| Anwendung: | 15-PGDH inhibitor |
| CAS | 459147-39-8 |
| MW: | 412.6 D |
ab 62,00 €
Anti-15-hydroxy Prostaglandin Dehydrogenase
Artikelnummer: Cay160615-1
NAD+-dependent 15-PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites, which have greatly reduced biological activity. Human NAD+-dependent 15-PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme...
| Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-Prostaglandin dehydrogenase 1, Anti-Short... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, guinea pig, baboon |
431,00 €