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SW033291
SW033291

Artikelnummer: TGM-T2121-1mg

Description: SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. Target: Dehydrogenase. Smiles: CCCCS(=O)c1sc2nc(cc(-c3ccccc3)c2c1N)-c1cccs1. References: Zhang Y, et al. Science. 2015, 348(6240), aaa2340.
Anwendung: 15-PGDH inhibitor
CAS 459147-39-8
MW: 412.59 D
ab 34,00 €
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CAY10397
CAY10397

Artikelnummer: TGM-T26956-1mg

Description: CAY10397, a selective inhibitor of 15-hydroxy PGDH, significantly suppresses endogenous 11-oxo-ETE production with a corresponding increase in 11(R)-HETE. Target: Others. Smiles: N(=NC1=CC=C(C(OCC)=O)C=C1)C2=CC(CC(O)=O)=C(O)C=C2. References: Liu X, Zhang S, Arora JS, Snyder NW, Shah SJ, Blair IA....
Anwendung: 15-hydroxy PGDH inhibitor
CAS 78028-01-0
MW: 328.32 D
ab 147,00 €
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ML-148
ML-148

Artikelnummer: TGM-T38163-100mg

Description: ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostaglandin-signaling pathways. Target: Dehydrogenase. Smiles:...
Anwendung: Potent, selective, competitive HPGD inhibitor
CAS 451496-96-1
MW: 319.4 D
ab 55,00 €
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15-PGDH-IN-1
15-PGDH-IN-1

Artikelnummer: TGM-T72950-10mg

Description: 15-PGDH-IN-1 is an orally active, potent inhibitor of 15-PGDH, exhibiting significant inhibitory activity against recombinant human 15-PGDH with an IC50 value of 3 nM. This compound is utilized in the research of tissue repair and regeneration. Target: Others. Smiles:...
Anwendung: 15-PGDH inhibitor
CAS 2241676-74-2
MW: 398.46 D
ab 166,00 €
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13,14-dihydro-15-keto Prostaglandin E2
13,14-dihydro-15-keto Prostaglandin E2

Artikelnummer: TGM-T84586-10mg

Description: 13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) serves as the predominant metabolite of PGE2 in plasma, created through a 15-keto PGE2 intermediate by the action of 15-oxo-PG Delta13 reductase. Unlike its precursor PGE2, this compound exhibits poor binding affinity towards EP2 and...
Schlagworte: 13,14-dihydro-15-keto PGE2
Anwendung: Bioactive lipid assays
CAS 363-23-5
MW: 352.5 D
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15-PGDH Protein, Human, Recombinant (His)
15-PGDH Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPY-01264-50ug

Description: 15-PGDH Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 29.7 kDa and the accession number is P15428-1.
Schlagworte: PGDH1, hydroxyprostaglandin dehydrogenase 15-(NAD), SDR36C1, PHOAR1, 15-PGDH, PGDH
MW: 29.7 kD
599,00 €
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15-PGDH Protein, Mouse, Recombinant (His)
15-PGDH Protein, Mouse, Recombinant (His)

Artikelnummer: TGM-TMPY-02273-50ug

Description: 15-PGDH Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30.6 kDa and the accession number is Q8VCC1.
Schlagworte: AV026552, hydroxyprostaglandin dehydrogenase 15-(NAD), 15-PGDH
MW: 30.6 kD
599,00 €
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13,14-dihydro-15-keto Prostaglandin E2
13,14-dihydro-15-keto Prostaglandin E2

Artikelnummer: Cay14650-1

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
Schlagworte: 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid
Anwendung: Bioactive lipid assays
CAS 363-23-5
MW: 352.5 D
ab 95,00 €
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Anti-HPGD
Anti-HPGD

Artikelnummer: CSB-PA994843.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HPGD. Antigen Species: Human
Schlagworte: Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin dehydrogenase [NAD(+)],...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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Anti-HPGD
Anti-HPGD

Artikelnummer: CSB-PA166476.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: HPGD. Antigen Species: Human
Schlagworte: Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin dehydrogenase [NAD(+)],...
Anwendung: ELISA, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 167,00 €
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SW033291
SW033291

Artikelnummer: Cay18040-5

The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo. It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection....
Schlagworte: 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine
Anwendung: 15-PGDH inhibitor
CAS 459147-39-8
MW: 412.6 D
ab 62,00 €
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Anti-15-hydroxy Prostaglandin Dehydrogenase
Anti-15-hydroxy Prostaglandin Dehydrogenase

Artikelnummer: Cay160615-1

NAD+-dependent 15-PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites, which have greatly reduced biological activity. Human NAD+-dependent 15-PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme...
Schlagworte: Anti-PGDH1, Anti-15-PGDH, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-Prostaglandin dehydrogenase 1, Anti-Short...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, bovine, guinea pig, baboon
431,00 €
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