Zu "K00031" wurden 147 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
(2R)-Octyl-alpha-hydroxyglutarate
Artikelnummer: Cay16366-10
alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
| Schlagworte: | (2R)-Octyl-2-HG, 2R-hydroxy-pentanedioic acid, 1-octyl ester |
| CAS | 1391194-67-4 |
| MW: | 260.3 D |
ab 39,00 €
Anti-IDH1
Artikelnummer: CSB-PA964946.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: IDH1. Antigen Species: Human
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH1, Anti-PICD, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase, Anti-Cytosolic... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Enasidenib
Artikelnummer: Cay21277-1
Enasidenib is an inhibitor of mutant isocitrate dehydrogenase 2 (IDH2, IC50 = 0.1 µM for IDH2 R140Q). It is selective for IDH2 R140Q over wild-type IDH2, wild-type IDH1, and IDH1 R132H (IC50s = 1.8, 0.45, and 48.4 µM, respectively). Enasidenib (0.1, 1, and 5 µM) inhibits production of D-2-hydroxyglutarate...
| Schlagworte: | AG-221, CC-90007,... |
| Anwendung: | Allosteric IDH2 inhibitor |
| CAS | 1446502-11-9 |
| MW: | 473.4 D |
34,00 €
![Isocitrate dehydrogenase [NADP] Cytoplasmic domain (Idh1), partial, mouse, recombinant](https://www.biomol.com/media/image/8b/d6/cd/CSB-EP010989MO-1_200x200.jpg "Isocitrate dehydrogenase [NADP] Cytoplasmic domain (Idh1), partial, mouse, recombinant")
Isocitrate dehydrogenase [NADP] Cytoplasmic domain...
Artikelnummer: CSB-EP010989MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 7-407aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GGSVVEMQGD EMTRIIWELI KEKLILPYVE LDLHSYDLGI ENRDATNDQV TKDAAEAIKK YNVGVKCATI TPDEKRVEEF KLKQMWKSPN GTIRNILGGT VFREAIICKN IPRLVTGWVK PIIIGRHAYG DQYRATDFVV...
| Schlagworte: | IDP, IDH, Idh1, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 49.2 kD |
ab 283,00 €
Anti-IDH1
Artikelnummer: CSB-PA005688.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH1, Anti-PICD, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase, Anti-Cytosolic... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
106,00 €
Anti-IDH2
Artikelnummer: CSB-PA148538.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: IDH2. Antigen Species: Human
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH2, Anti-ICD-M, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-IDH2
Artikelnummer: CSB-PA586287.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: IDH2. Antigen Species: Human
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH2, Anti-ICD-M, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-IDH1
Artikelnummer: CSB-PA826954.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: IDH1. Antigen Species: Human
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH1, Anti-PICD, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase, Anti-Cytosolic... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
IDH1(R132H) Assay Kit
Artikelnummer: BPS-79376
The IDH1(R132H) Assay Kit is designed to measure IDH1(R132H) activity for screening and profiling applications by measuring NADPH consumption.
| Schlagworte: | Isocitrate Dehydrogenase 1, IDH1, Oxalosuccinate Decarboxylase, IDHM, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
789,00 €
NADP-Isocitrate Dehydrogenase (NADP-IDH) Activity Assay Kit
Artikelnummer: E-BC-K554-M.96
Detection principle: Isocitrate dehydrogenase converts isocitrate to alpha- ketoglutaric acid, while converting NADP+ to NADPH. Under the action of electron coupling agents, the generated NADPH has a characteristic absorption peak at 450 nm. The activity of NADP-IDH can be calculated by measuring the change of...
| Schlagworte: | IDH, PICD, IDPc, IDH1, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Cytosolic NADP-isocitrate dehydrogenase,... |
416,00 €
Anti-IDH2 (R172K)
Artikelnummer: NB-26163
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Isocitrate dehydrogenase (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. The isocitrate and isopropylmalate dehydrogenases family has three members, IDH1, IDH2 and IDH3. IDH2 plays a role in intermediary...
| Schlagworte: | Anti-IDP, Anti-IDH, Anti-IDH2, Anti-ICD-M, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
717,00 €
Human ICD (IsocitRate Dehydrogenase) ELISA Kit
Artikelnummer: ELK-ELK8675.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ICD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ICD. Next,...
| Schlagworte: | IDH, IDH1, IDPc, PICD, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Cytosolic NADP-isocitrate dehydrogenase,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €