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LDH Cytotoxicity Assay Kit
Artikelnummer: Cay601170-96
Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
| Schlagworte: | Lactate Dehydrogenase Cytotoxicity Assay Kit |
| Anwendung: | Cell based assays |
| Spezies-Reaktivität: | broad |
ab 108,00 €
Anti-LDHA
Artikelnummer: E-D-AB-10210L.100
LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long...
| Schlagworte: | Anti-LDH-M, Anti-LDH-A, Anti-PIG19, Anti-LDH muscle subunit, Anti-L-lactate dehydrogenase A chain, Anti-Renal carcinoma... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 109,00 €
Sodium Oxamate
Artikelnummer: TGM-T19831-1g
Description: Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA. Sodium Oxamate has antitumor activity and induces cell cycle arrest and apoptosis. Target: Apoptosis, Dehydrogenase, CDK. Smiles: [Na+].NC(=O)C([O-])=O. References: Qiao T, et al. Inhibition of LDH-A by...
| Schlagworte: | Oxamic acid sodium salt, Aminooxoacetic acid sodium salt, oxamate sodium, SO |
| Anwendung: | Glycolysis disruptor, lactate dehydrogenase inhibitor |
| CAS | 565-73-1 |
| MW: | 111.03 D |
ab 31,00 €
FX-11
Artikelnummer: TGM-T15362-10mg
Description: FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 µM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor...
| Schlagworte: | LDHA Inhibitor FX11 |
| Anwendung: | LDH-A (lactate dehydrogenase-A) inhibitor |
| CAS | 213971-34-7 |
| MW: | 350.41 D |
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GSK2837808A
Artikelnummer: TGM-T15435-100mg
Description: GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 values of 1.9 nM for LDHA and 14 nM for LDHB. Target: Dehydrogenase. Smiles: COc1ncc(-c2ccc3c(Nc4cc(Oc5cc(F)cc(F)c5)cc(c4)C(O)=O)c(cnc3c2)S(=O)(=O)NC2CC2)c(OC)n1. References: Billiard J, et al. Quinoline...
| Anwendung: | Potent, selective cell-permeable LDHA inhibitor |
| CAS | 1445879-21-9 |
| MW: | 649.62 D |
ab 42,00 €
LDHA-IN-4
Artikelnummer: TGM-T3175-10mg
Description: LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 µM. Target: Dehydrogenase. Smiles: Cc1nc2ccc(NC(=O)CCNC(=O)CCCc3ccc(CC(C(O)=O)C(O)=O)cc3)cc2s1....
| Schlagworte: | AZ33, AZ-33, LDHA Inhibitor, AZ 33 |
| Anwendung: | LDHA inhibitor |
| CAS | 1370290-34-8 |
| MW: | 497.56 D |
ab 45,00 €
(R)-GNE-140
Artikelnummer: TGM-T4295-100mg
Description: (R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer. Target: Dehydrogenase. Smiles: OC1=C(Sc2ccccc2Cl)C(=O)N[C@@](C1)(c1ccsc1)c1ccc(cc1)N1CCOCC1. References: Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate...
| Schlagworte: | GNE-140 |
| Anwendung: | LDHA/LDHB inhibitor |
| CAS | 2003234-63-5 |
| MW: | 499.04 D |
ab 67,00 €
LDHA Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00724-10ug
Description: L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr...
| Schlagworte: | LDH Muscle Subunit, Renal Carcinoma Antigen NY-REN-59, Cell Proliferation-Inducing Gene 19 Protein, LDH-M, LDH-A, LDHA,... |
| MW: | 37 kD |
ab 181,00 €
LDHB Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPJ-00797-10ug
Description: L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C, members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate...
| Schlagworte: | LDHB, L-lactate Dehydrogenase B Chain, LDH Heart Subunit, Renal Carcinoma Antigen NY-REN-46, LDH-B, LDH-H |
| MW: | 37 kD |
ab 181,00 €
LDHA Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPY-00010-100ug
Description: LDHA Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P06151.
| Schlagworte: | Ldh1, lactate dehydrogenase A, Ldhm, l7R2 |
| MW: | 36.5 kD |
461,00 €
LDHC Protein, Human, Recombinant (His & SUMO)
Artikelnummer: TGM-TMPH-01614-100ug
Description: Possible role in sperm motility.
| Schlagworte: | LDH-X, Cancer/testis antigen 32, L-lactate dehydrogenase C chain, LDH testis subunit, LDHC |
| MW: | 52.2 kD |
ab 281,00 €
LDHA Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPY-04241-100ug
Description: LDHA Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 38.7 kDa and the accession number is B5DEN4.
| Schlagworte: | lactate dehydrogenase A |
| MW: | 38.7 kD |
599,00 €