Zu "96201-88-6" wurden 2 Artikel gefunden!
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Bipenquinate
Artikelnummer: TGM-T8332-100mg
Description: Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis. Target: Dehydrogenase. Smiles: [Na+].Cc1c(nc2ccc(F)cc2c1C([O-])=O)-c1ccc(cc1)-c1ccccc1F. References: Li S F , Gong M J , Sun Y F , et al. Antiviral...
| Anwendung: | Targets dihydroorotate dehydrogenase [EC:1.3.5.2] (DHODH, pyrD) |
| CAS | 96201-88-6 |
| MW: | 397.36 D |
ab 31,00 €
Brequinar (sodium salt)
Artikelnummer: Cay36183-10
Brequinar is an inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = ~20 nM), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. Brequinar is selective for DHODH over a panel of greater than 400 kinases at 100 nM. It induces differentiation of ER-HoxA9, U937, and THP-1 cells...
| Schlagworte: | DuP-785, NSC 368390, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid, monosodium salt |
| Anwendung: | DHODH inhibitor |
| CAS | 96201-88-6 |
| MW: | 397.4 D |
ab 92,00 €
