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Brequinar
Artikelnummer: TGM-T5013-100mg
Description: Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses. Target: Dehydrogenase, DNA/RNA Synthesis, Virus Protease. Smiles: Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F. References: Qing M, et al. Characterization of...
| Schlagworte: | Bipenquinate, NSC 368390, DUP785 |
| Anwendung: | DHODH inhibitor |
| CAS | 96187-53-0 |
| MW: | 375.37 D |
ab 41,00 €
Brequinar
Artikelnummer: Cay24445-1
Brequinar is an inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = ~20 nM), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. Brequinar is selective for DHODH over a panel of greater than 400 kinases at 100 nM. It induces differentiation of ER-HoxA9, U937, and THP-1 cells...
| Schlagworte: | NSC 368390, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid |
| Anwendung: | DHODH inhibitor |
| CAS | 96187-53-0 |
| MW: | 375.4 D |
ab 43,00 €
