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Devimistat
Artikelnummer: TGM-T6157-100mg
Description: Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and alpha-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potential chemopreventive and antineoplastic activities, and has been used in trials...
| Schlagworte: | 6,8-Bis(benzylthio)octanoic acid, CPI613, CPI 613, CPI-613 |
| Anwendung: | alpha-ketoglutarate dehydrogenase inhibitor |
| CAS | 95809-78-2 |
| MW: | 388.59 D |
ab 54,00 €
CPI-613
Artikelnummer: Cay16981-5
CPI-613 is a lipoic acid analog that inhibits alpha-ketoglutarate dehydrogenase, particularly in tumor cells. At 60-240 µM, CPI-613 induces a strong mitochondrial burst of reactive oxygen species, resulting in cell death. By disrupting mitochondrial metabolism, CPI-613 demonstrates both in vitro and in vivo...
| Schlagworte: | 6,8-bis[(phenylmethyl)thio]-octanoic acid |
| Anwendung: | alpha-ketoglutarate dehydrogenase inhibitor |
| CAS | 95809-78-2 |
| MW: | 388.6 D |
ab 54,00 €
