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BCI hydrochloride
Artikelnummer: TGM-T10486L-2mg
Description: BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 µM in cells, respectively. BCI hydrochloride does not inhibit DUSP5. BCI hydrochloride is an allosteric inhibitor of dual specificity phosphatase (DUSP). Target: Others. Smiles: Cl.O=C1C(=Cc2ccccc2)C(NC2CCCCC2)c2ccccc12 ,...
| Schlagworte: | (E)-BCI hydrochloride |
| CAS | 95130-23-7 |
| MW: | 353.89 D |
88,00 €
BCI (hydrochloride)
Artikelnummer: Cay21945-1
BCI is an inhibitor of dual specificity phosphatase 6 (DUSP6) and DUSP1. (E/Z)-BCI (0.5-2 µM) inhibits LPS-induced expression of Dusp6 in a concentration-dependent manner and increases nuclear protein levels of Nrf2 in RAW 264.7 macrophages. It also inhibits LPS-induced increases in the production of IL-1beta, IL-6,...
| Schlagworte: | 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1H-inden-1-one, monohydrochloride |
| Anwendung: | Dusp6 inhibitor |
| CAS | 95130-23-7 |
| MW: | 353.9 D |
ab 61,00 €
