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ML365
Artikelnummer: TGM-T4316-100mg
Description: ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3). Target: Potassium Channel. Smiles: COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1. References: Zou B, et al. ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel. Probe Reports from the...
| Anwendung: | KCNK3 / TASK-1 potassium channel blocker |
| CAS | 947914-18-3 |
| MW: | 360.41 D |
ab 31,00 €
ML-365
Artikelnummer: Cay24666-1
ML-365 is a bis-amide TASK-1 potassium channel blocker (IC50 = 16 nM). It is selective for TASK-1 over TASK-3 channels in a QPatch assay (IC50 = 990 nM). It also acts as an antagonist of the metabotropic glutamate receptor mGluR5 (IC50 = 1.35 µM).Formal Name: 2-methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]-benzamide....
| Schlagworte: | 2-methoxy-N-[3-[(3-methylbenzoyl)amino]phenyl]-benzamide |
| Anwendung: | KCNK3 / TASK-1 potassium channel blocker |
| CAS | 947914-18-3 |
| MW: | 360.4 D |
ab 52,00 €
