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Mycro 3
Artikelnummer: TGM-T4367-100mg
Description: Mycro 3 is potent and selective for c-Myc in whole cell assays. Target: Autophagy, c-Myc. Smiles: CCOC(=O)c1cnn(c1NC(=O)c1cc2nc(cc(n2n1)C(F)(F)Cl)-c1ccco1)-c1ccccc1. References: Chen BJ, et al. Small molecules targeting c-Myc oncogene: promising anti-cancer therapeutics. Int J Biol Sci. 2014 Sep...
| Schlagworte: | Mycro-3 |
| Anwendung: | C-Myc-Max protein-protein interaction inhibitor |
| CAS | 944547-46-0 |
| MW: | 526.88 D |
ab 45,00 €
Mycro 3
Artikelnummer: Cay37767-1
Mycro 3 is an inhibitor of the protein-protein interaction between c-Myc and c-Myc associated protein (Max, IC50 = 40 µM). It is also an inhibitor of Max dimerization (IC50 = 88 µM). Mycro 3 selectively reduces the viability of c-Myc-expressing TGR-1 fibroblasts over c-Myc-null HO15.19 fibroblasts (IC50s = 0.25 and...
| Schlagworte: | 5-[[[7-(chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-1H-pyrazole-4-carboxylic... |
| Anwendung: | C-Myc-Max protein-protein interaction inhibitor |
| CAS | 944547-46-0 |
| MW: | 526.9 D |
ab 111,00 €
