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GSK1016790A
GSK1016790A

Artikelnummer: TGM-T6848-1mg

Description: GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells. Target: TRP/TRPV Channel, Calcium Channel. Smiles: CC(C)C[C@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCN(CC1)C(=O)[C@H](CO)NS(=O)(=O)c1ccc(Cl)cc1Cl....
Schlagworte: GSK101
Anwendung: TRPV4 agonist
CAS 942206-85-1
MW: 655.61 D
ab 31,00 €
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GSK1016790A
GSK1016790A

Artikelnummer: Cay17289-5

Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel thought to be involved in osmoregulation, hyperalgesia, and control of epithelial cell volume. GSK1016790A is a TRPV4 agonist that has been reported to elicit calcium influx in HEK cells expressing mouse or human TRPV4 (EC50s = 18 and...
Schlagworte: N-[(1S)-1-[[4-[(2S)-2-[[(2,4-dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]-...
Anwendung: TRPV4 agonist
CAS 942206-85-1
MW: 655.6 D
ab 44,00 €
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