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NVP-BHG712
NVP-BHG712

Artikelnummer: TGM-T6348-100mg

Description: NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition, also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 µM, 1.266 µM and 1.667 µM, respectively. Target: Ephrin Receptor, Bcr-Abl, Src, Raf. Smiles:...
Anwendung: EphB4 kinase autophosphorylation inhibitor
CAS 940310-85-0
MW: 503.48 D
ab 31,00 €
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NVP-BHG712
NVP-BHG712

Artikelnummer: Cay18489-5

The EphB4 receptor tyrosine kinase (cloned from erythropoietin-producing hepatocellular carcinoma) and its ligand ephrinB2 play an important role in embryonic vessel development and vascular remodeling. Signaling from this pair is also involved in tumor angiogenesis. NVP-BHG712 is an orally bioavailable inhibitor of...
Schlagworte: 4-methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]-benzamide
Anwendung: EphB4 kinase autophosphorylation inhibitor
CAS 940310-85-0
MW: 503.5 D
ab 52,00 €
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NVP-BHG712
NVP-BHG712

Artikelnummer: LKT-N8460.1

NVP-BHG712 is a specific inhibitor of c-Raf, c-Src and c-Abl
Schlagworte: 4-methyl-3-(1-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-N-(3-(trifluoromethyl)phenyl)benzamide -
Anwendung: c-Raf / c-SRC / c-Abl inhibitor
CAS 940310-85-0
MW: 503.48 D
ab 98,00 €
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