Zu "939805-30-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
EOC317
Artikelnummer: TGM-T4318-100mg
Description: EOC317 (ACTB-1003) is an oral kinase inhibitor with IC50 values of 6 nM, 2 nM, and 4 nM for FGFR1, VEGFR2, and Tie-2, respectively. Target: FGFR, VEGFR, Tie-2. Smiles: COCc1c(CN2CCOCC2)n2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)c(F)c1. References: Patel K, et al. ACTB-1003: An oral kinase...
| Schlagworte: | ACTB1003, ACTB 1003, ACTB-1003 |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 939805-30-8 |
| MW: | 591.53 D |
ab 93,00 €
ACTB-1003
Artikelnummer: Cay30069-1
ACTB-1003 is a multi-kinase inhibitor (IC50s = 6, 2, 4, 5, and 32 nM for FGFR1, VEGFR2, Tie-2, RSK, and p70S6K, respectively). It inhibits growth of OPM2 human multiple myeloma and murine Ba/F3-TEL-FGFR1 leukemia cells in vitro. ACTB-1003 inhibits tumor angiogenesis in an H460 mouse xenograft model. It also reduces...
| Schlagworte: | N-[4-[4-amino-6-(methoxymethyl)-7-(4-morpholinylmethyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl]-2-fluorophenyl]-N'-[2-fluoro-5-(... |
| Anwendung: | Multi-kinase inhibitor |
| CAS | 939805-30-8 |
| MW: | 591.5 D |
ab 67,00 €
