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TG101209
Artikelnummer: TGM-T3065-100mg
Description: TG101209 is a selective JAK2 inhibitor with an IC50 of 6 nM. Target: Autophagy, FLT, Apoptosis, c-RET, JAK. Smiles: CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1. References: Pardanani A, et al, Leukemia, 2007, 21(8), 1658-1668.
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 936091-14-4 |
| MW: | 509.67 D |
ab 40,00 €
TG101209
Artikelnummer: Cay14696-1
TG101209 is a potent inhibitor of the tyrosine kinases janus kinase (JAK) 2, FMS-like tyrosine kinase 3, proto-oncogene RET, and JAK3 (IC50 = 6, 25, 17, and 169 nM, respectively). Through these effects, it induces cell cycle arrest and apoptosis in leukemic cell lines and CD45+ myeloma cells.Formal Name:...
| Schlagworte: | N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-benzenesulfonamide |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 936091-14-4 |
| MW: | 509.7 D |
ab 60,00 €
TG101209
Artikelnummer: SYN-1103-M001
Soluble in DMSO or ethanol. TG101209 is a potent, small molecule JAK2-selective kinase inhibitor with IC(50) values of 6, 25, 17 and 169nM for JAK2, FLT3, RET and JAK3. Target: JAK2 , Kinase Group: PTK , Substrate: Tyrosine
| Schlagworte: | TG-101209 |
| Anwendung: | JAK2 inhibitor |
| CAS | 936091-14-4 |
| MW: | 509,7 D |
ab 152,00 €
