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Cobimetinib
Artikelnummer: Cay19563-1
Cobimetinib is a potent, orally available inhibitor of MEK1 (IC50 = 4.2 nM). It shows more than 100-fold selectivity for MEK when tested against a panel of more than 100 serine-threonine and tyrosine kinases. Cobimetinib induces differentiation and apoptosis in cancer cell lines and is more effective when combined...
| Schlagworte: | GDC-0973, RG-7420, XL518,... |
| Anwendung: | Antineoplastic, MEK inhibitor |
| CAS | 934660-93-2 |
| MW: | 531.3 D |
ab 66,00 €
GDC-0973
Artikelnummer: LKT-G124084.25
MEK1 inhibitor.
| Schlagworte: | GDC 0973, GDC0973, XL-518, XL 518, XL518, Cobimetinib, RG-7420, RG 7420, RG7420 |
| Anwendung: | Mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase (MEK) inhibitor |
| CAS | 934660-93-2 |
| MW: | 531.32 D |
ab 108,00 €
