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Raxatrigine (hydrochloride)
Artikelnummer: Cay23490-5
Raxatrigine is an inhibitor of voltage-gated sodium channels (Nav, IC50s = 22, 13, 23, 10, 84, 15, 32, and 6 µM for Nav1.1-Nav1.8 channels in a FLIPR membrane potential assay using HEK293 cells). Its activity is state-dependent at the Nav1.7 channel, with a nine-fold increase in potency for the open/inactivated...
| Schlagworte: | GSK1014802A, (2S)-5R-[4-[(2-fluorophenyl)methoxy]phenyl]-2-pyrrolidinecarboxamide, monohydrochloride |
| Anwendung: | Voltage-gated sodium channel inhibitor |
| CAS | 934240-31-0 |
| MW: | 350.8 D |
ab 50,00 €
