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S107
Artikelnummer: TGM-T3438-100mg
Description: S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. Target: Others. Smiles: COc1ccc2SCCN(C)Cc2c1. References: Lehnart SE, et al. Leaky Ca
| Anwendung: | RyR1-FKBP12 protein-protein interaction stabilizer |
| CAS | 927871-76-9 |
| MW: | 209.31 D |
ab 39,00 €
S107
Artikelnummer: Cay13253-5
S107 is a stabilizer of the protein-protein interaction between ryanodine receptor 1 (RyR1) and FK-506 binding protein 1A (FKBP12). It stabilizes sarcoplasmic reticulum RyR1 channels by decreasing the dissociation of FKBP12 in isolated mouse muscle fibers. S107 (50 and 100 µM) also reduces neurite growth and length...
| Schlagworte: | 2,3,4,5-tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine |
| Anwendung: | RyR1-FKBP12 protein-protein interaction stabilizer |
| CAS | 927871-76-9 |
| MW: | 209.3 D |
ab 109,00 €
