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Opicapone
Artikelnummer: TGM-T16398-100mg
Description: Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 µM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. Target: Transferase. Smiles:...
| Schlagworte: | BIA 9-1067 |
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 923287-50-7 |
| MW: | 413.17 D |
ab 60,00 €
Opicapone
Artikelnummer: Cay34253-10
Opicapone is a peripherally selective inhibitor of catechol-O-methyltransferase (COMT). It inhibits COMT activity in rat liver, but not brain, homogenates (ED50 = 1.05 mg/kg). Opicapone (3 mg/kg) increases plasma levels of L-DOPA (Cay-13248) and reduces plasma levels of 3-O-methyl-DOPA (3-OMD) when administered in...
| Schlagworte: | BIA 9-1067, 5-[3-(2,5-dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-1,2-benzenediol |
| Anwendung: | COMT inhibitor |
| CAS | 923287-50-7 |
| MW: | 413.2 D |
ab 36,00 €
