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OF-1
Artikelnummer: TGM-T2127-100mg
Description: OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain. Target: Epigenetic Reader Domain. Smiles: COc1cc2n(C)c(=O)n(C)c2cc1NS(=O)(=O)c1ccc(Br)cc1C. References: Structural Genomics Consortium (SGC).
| CAS | 919973-83-4 |
| MW: | 440.31 D |
ab 33,00 €
OF-1
Artikelnummer: Cay17124-5
OF-1 is a chemical probe for the bromodomains of the Bromodomain and PHD Finger-containing (BRPF) family of proteins. It binds BRPF1B, BRPF2, and BRPF3 with Kd values of 0.1, 0.5, and 2.4 µM, respectively, as determined by isothermal titration calorimetry. OF-1 increases thermal stability of full length BRPF1B at 1...
| Schlagworte: | 4-bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-benzenesulfonamide |
| Anwendung: | BRPF probe |
| CAS | 919973-83-4 |
| MW: | 440.3 D |
ab 67,00 €
