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AZD1283
Artikelnummer: TGM-T3536-100mg
Description: AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 µg/kg/min, respectively. The doses induced the increase...
| Anwendung: | P2Y purinoceptor 12, P2Y12 antagonist |
| CAS | 919351-41-0 |
| MW: | 470.54 D |
ab 32,00 €
AZD 1283
Artikelnummer: Cay27649-1
AZD 1283 is an antagonist of the purinergic P2Y12 receptor (IC50 = 25 nM in a GTPgammaS assay in CHO cells). It selectively binds to the P2Y12 receptor (Kd = 11 nM) over more than 100 enzymes, receptors, and ion channels, including the P2Y1, platelet activating factor (PAF), and thromboxane A2 receptors, at 10 µM.,...
| Schlagworte: | 6-[4-[[(Benzylsulfonyl)amino]carbonyl]piperidin-1-yl]-5-cyano-2-methylnicotinic acid ethyl ester, AZD 1283,... |
| Anwendung: | P2Y purinoceptor 12, P2Y12 antagonist |
| CAS | 919351-41-0 |
| MW: | 470.5 D |
ab 43,00 €
