Zu "917837-54-8" wurden 2 Artikel gefunden!
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CCMI
Artikelnummer: TGM-T7422-100mg
Description: CCMI (AVL-3288) is a potent and selective modulator of alpha7 nAChR-positive allosteric sites. Target: AChR. Smiles: Cc1cc(on1)C(=C/Nc1ccc(Cl)cc1)\C(=O)Nc1ccc(Cl)cc1. References: Ng H J , Whittemore E R , Tran M B , et al. Nootropic ?7 nicotinic receptor allosteric modulator derived from GABAA receptor...
| Schlagworte: | AVL-3288 |
| Anwendung: | Alpha7 nAChR positive allosteric modulator |
| CAS | 917837-54-8 |
| MW: | 388.25 D |
ab 39,00 €
CCMI
Artikelnummer: Cay37571-25
CCMI is a positive allosteric modulator (PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-, nicotine-, or choline-induced currents in Xenopus oocytes expressing recombinant human alpha7 nAChRs (EC50s = 0.7, 0.6, and 0.5 µM, respectively). In vivo, CCMI (0.3 and 1 mg/kg, i.v.) improves...
| Schlagworte: | AVL-3288, XY-4083, N-(4-chlorophenyl)-alpha-[[(4-chlorophenyl)amino]methylene]-3-methyl-5-isoxazoleacetamide |
| Anwendung: | Alpha7 nAChR positive allosteric modulator |
| CAS | 917837-54-8 |
| MW: | 388.3 D |
ab 35,00 €
