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ML348
Artikelnummer: TGM-T3439-100mg
Description: ML348 (GNF-Pf-1127) is a selective, reversible inhibitor of lysophospholipase 1 (LYPLA1) with an IC50 of 210 nM. Target: Phospholipase, Others. Smiles: FC(F)(F)c1ccc(Cl)c(NC(=O)CN2CCN(CC2)C(=O)c2ccco2)c1. References: Adibekian A, et al. National Center for Biotechnology Information (US), 2010-.2013 Apr...
| Schlagworte: | GNF-Pf-1127 |
| Anwendung: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.79 D |
ab 40,00 €
ML-348
Artikelnummer: Cay18523-1
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML-348 is a reversible LYPLA1...
| Schlagworte: | CID 3238952, SID 160654487, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide |
| Anwendung: | Reversible LYPLA1 inhibitor |
| CAS | 899713-86-1 |
| MW: | 415.8 D |
ab 44,00 €
