Zu "898800-26-5" wurden 2 Artikel gefunden!
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AZ876
Artikelnummer: TGM-T5178-100mg
Description: AZ876 is a potent, highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRalpha and hLXRbeta respectively. Target: Liver X Receptor. Smiles: CC(C)(C)N1C(=O)C(Nc2ccc(cc2)N2CCCCC2)=C(c2ccccc2)S1(=O)=O. References: van der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876,...
| Anwendung: | LXR agonist |
| CAS | 898800-26-5 |
| MW: | 439.57 D |
ab 45,00 €
AZ876
Artikelnummer: Cay34413-5
AZ876 is a liver X receptor (LXR) agonist. It activates LXRalpha and LXRbeta in a transactivation assay in U2OS osteosarcoma cells (EC50 = 6 and 73 nM, respectively). AZ876 reduces phenylephrine-induced increases in cell size and protein synthesis in isolated neonatal rat ventricular myocytes. It decreases plasma...
| Schlagworte: | 2-(1,1-dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone, 1,1-dioxide |
| Anwendung: | LXR agonist |
| CAS | 898800-26-5 |
| MW: | 439.6 D |
ab 65,00 €
