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LY2334737
Artikelnummer: TGM-T4061-100mg
Description: LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity. Target: Virus Protease, Others, Nucleoside Antimetabolite/Analog. Smiles: CCCC(CCC)C(=O)Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1. References: Pratt SE, et al. Human carboxylesterase-2 hydrolyzes the prodrug of...
| Anwendung: | Gemcitabine prodrug form |
| CAS | 892128-60-8 |
| MW: | 389.39 D |
ab 63,00 €
LY2334737
Artikelnummer: Cay37425-1
LY2334737 is a prodrug form of the nucleoside analog gemcitabine (Cay-11690, Cay-9003096). In vivo, LY2334737 (8 mg/kg) reduces tumor volume in an MDA321-LM2-4175 breast cancer mouse xenograft model and increases survival in an SKOV3 ovarian cancer mouse xenograft model.Formal Name:...
| Schlagworte: | 2'-deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)-cytidine |
| Anwendung: | Gemcitabine prodrug form |
| CAS | 892128-60-8 |
| MW: | 389.4 D |
ab 35,00 €
