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DC-05
Artikelnummer: TGM-T15080-100mg
Description: DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 µM and 1.09 µM, respectively). Target: Histone Methyltransferase, DNA Methyltransferase. Smiles: OC(CNCCc1c[nH]c2ccccc12)Cn1c2ccccc2c2ccccc12. References: Chen S, et al. Identifying novel selective non-nucleoside DNA...
| Anwendung: | Non-nucleoside DNMT1 inhibitor |
| CAS | 890643-16-0 |
| MW: | 383.49 D |
ab 131,00 €
DC-05
Artikelnummer: Cay36584-1
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1, IC50 = 10.3 µM). It is selective for DNMT1 over DNMT3A and DNMT3B (IC50s = >200 µM), as well as the additional methyltransferases G9a, SUV39H1, MLL1, SET7/9, and PRMT1 (IC50s = >150, >150, >150, >150, and 37.1 µM, respectively). DC-05 (2.5-10 µM) reduces...
| Schlagworte: | alpha-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-9H-carbazole-9-ethanol |
| Anwendung: | Non-nucleoside DNMT1 inhibitor |
| CAS | 890643-16-0 |
| MW: | 383.5 D |
ab 61,00 €
