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BFH772
Artikelnummer: TGM-T3599-100mg
Description: BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation of RET, PDGFR, and KIT kinases, with IC50 values ranging between 30 and 160 nM....
| Schlagworte: | BFH-722 |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 890128-81-1 |
| MW: | 439.39 D |
ab 40,00 €
BFH772
Artikelnummer: Cay21386-1
BFH772 is an inhibitor of VEGF receptor 2 (VEGFR2, IC50 = 0.0027 µM for the human receptor). It is selective for human VEGFR2 over mouse VEGFR2 and human VEGFR1 and VEGFR3 (IC50s = 1.5, 1.7, and 1.1 µM, respectively), as well as 40-fold selective over B-RAF, RET, and Tie2. BFH772 inhibits VEGF-induced proliferation...
| Schlagworte: | 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 890128-81-1 |
| MW: | 439.4 D |
ab 53,00 €
