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LY2119620
Artikelnummer: TGM-T6575-100mg
Description: LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. Target: AChR. Smiles: CN1CCN(CC1)C(=O)COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl. References: Croy CH, et al. Mol Pharmacol. 2014, 86(1), 106-115.
| Anwendung: | Muscarinic acetylcholine receptor M2 / M4 positive allosteric modulator (PAM) |
| CAS | 886047-22-9 |
| MW: | 437.94 D |
ab 52,00 €
LY2119620
Artikelnummer: Cay26373-5
LY2119620 is a positive allosteric modulator of the M2 and M4 muscarinic acetylcholine receptors (mAChRs). It binds to allosteric sites on M2 and M4 receptors with KB values ranging from 1.8 to 3.4 µM. LY2119620 potentiates the activity of the AChR agonist acetylcholine (ACh, Cay-23829) and the mAChR agonists...
| Schlagworte: | 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide |
| Anwendung: | Muscarinic acetylcholine receptor M2 / M4 positive allosteric modulator (PAM) |
| CAS | 886047-22-9 |
| MW: | 437.9 D |
ab 98,00 €
