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SBI-115
Artikelnummer: TGM-T7428-100mg
Description: SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5. Target: GPCR19. Smiles: CCS(=O)(=O)c1ncc(Cl)c(n1)C(=O)Oc1cccc(C)c1. References: Masyuk TV, Masyuk AI, Lorenzo Pisarello M,et al.TGR5 contributes to hepatic cystogenesis in rodents...
| Anwendung: | GPBAR1 antagonist |
| CAS | 882366-16-7 |
| MW: | 340.78 D |
ab 48,00 €
SBI-115
Artikelnummer: Cay39168-10
SBI-115 is an antagonist of G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5. It inhibits taurolithocholic acid-induced increases in cAMP levels in, and proliferation of, cholangiocytes isolated from patients with autosomal dominant polycystic kidney disease when used at concentrations of 100 and...
| Schlagworte: | 5-chloro-2-(ethylsulfonyl)-4-pyrimidinecarboxylic acid 3-methylphenyl ester |
| Anwendung: | GPBAR1 antagonist |
| CAS | 882366-16-7 |
| MW: | 340.8 D |
ab 74,00 €
