Zu "875787-07-8" wurden 2 Artikel gefunden!
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LXR-623
Artikelnummer: TGM-T1783-100mg
Description: LXR-623 (WAY 252623) is an orally bioavailable and highly specifical synthetic modulator of LXR. Target: Liver X Receptor. Smiles: Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F. References: Katz A, et al. J Clin Pharmacol. 2009, 49(6):643-9.
| Schlagworte: | WAY 252623, LXR623 |
| Anwendung: | LXR agonist |
| CAS | 875787-07-8 |
| MW: | 422.78 D |
ab 46,00 €
LXR-623
Artikelnummer: Cay21117-1
LXR-623 is a liver X receptor (LXR) modulator that acts as a partial agonist at LXRalpha and a full agonist at LXRbeta (IC50s = 179 and 24 nM, respectively). It is orally bioavailable and readily passes the blood-brain barrier. LXR-623 is anti-atherogenic in animal models of atherosclerosis, showing synergistic...
| Schlagworte: | WAY-252623, 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole |
| Anwendung: | LXR agonist |
| CAS | 875787-07-8 |
| MW: | 422.8 D |
ab 44,00 €
