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Quisinostat
Artikelnummer: TGM-T6055-100mg
Description: Quisinostat (JNJ-26481585) (JNJ-26481585) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM, modest potent to HDACs 2, 4, 10, and 11, greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Target: HDAC, Apoptosis,...
| Schlagworte: | JNJ-26481585 |
| Anwendung: | Antineoplastic, Histone deacetylase inhibitor |
| CAS | 875320-29-9 |
| MW: | 394.47 D |
ab 55,00 €
Quisinostat
Artikelnummer: SYN-3029-M001
Quisinostat (JNJ-26481585) is a novel second-generation panHDAC inhibitor of HDAC1, 2, 4, 10 and 11. Its highest potency is against HDAC1 with an IC50 of 0.11nM. It has only modest potency against HDACs 2, 4, 10, and 11 (IC50 ranging from 0.33nM to 0.64nM). It has low activity against HDACs 3, 5, 8, and 9 and its...
| Schlagworte: | JNJ-26481585 |
| Anwendung: | pan-HDAC inhibitor (HDAC1, 2, 4, 10, 11) |
| CAS | 875320-29-9 |
| MW: | 394.5 D |
ab 139,00 €
Selonsertib Hydrochloride
Artikelnummer: SYN-1229-M100
Solid. Soluble in DMSO or ethanol. LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
| Schlagworte: | LY-2784544 |
| Anwendung: | JAK2 inhibitor |
| CAS | 875320-29-9 |
| MW: | 469,9 D |
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