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GDC-0152
Artikelnummer: TGM-T6299-10mg
Description: GDC-0152 is a potent inhibitor of IAPs. Target: IAP. Smiles: C([C@@H](NC([C@@H](NC)C)=O)[C@@H]1CCCCC1)(=O)N2[C@H](C(NC3=C(N=NS3)C4=CC=CC=C4)=O)CCC2. References: Flygare JA, et al. J Med Chem, 2012, 55(9), 4101-4113.
| Schlagworte: | GDC0152 |
| Anwendung: | Caspase activator |
| CAS | 873652-48-3 |
| MW: | 498.64 D |
ab 37,00 €
GDC-0152
Artikelnummer: Cay17810-10
Inhibitor of apoptosis proteins (IAPs), which block various signaling pathways leading to apoptotic cell death, are commonly over-expressed in cancer cells. GDC-0152 is a potent inhibitor of specific IAPs that binds baculoviral IAP repeat (BIR) domains (Kis = 28, 14, 17, and 43 nM for XIAP BIR3, NL-IAP BIR, BIRC2...
| Schlagworte: | N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide |
| Anwendung: | Caspase activator |
| CAS | 873652-48-3 |
| MW: | 498.6 D |
ab 61,00 €
GDC-0152 Free Base
Artikelnummer: LKT-G124086.1
GDC-0152 is an X-linked inhibitor of apoptosis protein (XIAP). GDC-0152 induces apoptosis in several cell lines including HL-60, NB4, osteosarcoma, glioblastomas among others.
| Schlagworte: | GDC0152, GDC 0152, N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide |
| Anwendung: | Apoptosis inducer |
| CAS | 873652-48-3 |
| MW: | 498.65 D |
ab 81,00 €
