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T-26c
Artikelnummer: TGM-T5361-100mg
Description: T-26c is a highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM. Target: MMP. Smiles: COc1cccc(CNC(=O)c2nc(=O)c3c(COCc4ccc(cc4)C(O)=O)csc3[nH]2)c1. References: Nara H, et al. Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at...
| Anwendung: | Selective matrix metalloproteinase-13 (MMP-13) inhibitor |
| CAS | 869296-13-9 |
| MW: | 479.51 D |
ab 42,00 €
T-26c
Artikelnummer: Cay19962-1
T-26c is a selective inhibitor of matrix metalloproteinase-13 (MMP-13, IC50 = 0.0069 nM). It is selective for MMP-13 over MMP-1, -2, -3, -7, -8, -9, -10, and -14 (IC50s = >18 nM). T-26c inhibits IL-1beta- and oncostatin M-induced collagen degradation in bovine nasal septum cartilage explants by 87.4% when used at a...
| Schlagworte: | 4-[[[1,4-dihydro-2-[[[(3-methoxyphenyl)methyl]amino]carbonyl]-4-oxothieno[2,3-d]pyrimidin-5-yl]methoxy]methyl]-benzoic acid |
| Anwendung: | Selective matrix metalloproteinase-13 (MMP-13) inhibitor |
| CAS | 869296-13-9 |
| MW: | 479.5 D |
ab 53,00 €
