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SB 203580 hydrochloride
Artikelnummer: TGM-T21675-10mg
Description: Adezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, with IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38beta2. This compound also inhibits LCK, GSK3beta, and PKBalpha with IC50 values 100-500 times higher than those for SAPK2a/p38. Additionally,...
| CAS | 869185-85-3 |
| MW: | 413.9 D |
ab 37,00 €
SB 203580 (hydrochloride)
Artikelnummer: Cay13344-5
Mitogen-activated protein kinases (MAPKs) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
| Schlagworte: | PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine, monohydrochloride |
| Anwendung: | p38 MAPK inhibitor |
| CAS | 869185-85-3 |
| MW: | 413.9 D |
ab 152,00 €
